
Senior Radiopharmaceutical Specialist
3 days ago
Job Description:
The Production Radiochemist at our institution is responsible for the routine production of radiopharmaceuticals inside a Clean Room environment, in compliance with Good Manufacturing Practice (GMP). The Radiochemist will assist in method development and validation of new radiopharmaceuticals, including preparation of standard operating procedures (SOPs) and other quality documentation.
With strong technical and analytical expertise, the Production Radiochemist maintains high operational uptime, ensures regulatory compliance, and upholds patient and product safety standards.
Key Responsibilities:
- Perform radiolabelling of peptides, antibodies, or small molecules using radionuclides such as Lu-177, Ga-68, F-18, etc.
- Prepare and review batch records, lab notebooks, SOPs, and other QC documents.
- Assist with emergency maintenance/calibration of radiochemistry synthesis and dispensing modules.
- Support deviation investigations, CAPAs, and change control implementations as needed.
- Perform ad-hoc clean room activities, including cleaning of rooms, stock inventory, and environmental monitoring.
- Safe handling of radioactive materials, including hazardous waste disposal.
- Work flexible hours, shifts, or weekends based on production schedules and isotope half-lives.
- Perform any other duties assigned by the Head of Department in accordance with GMP and safety regulations.
Qualifications and Skills:
- A minimum of BSc degree in Synthetic Organic/ Inorganic/ Medical Chemistry or a related science discipline.
- Practical experiences in general laboratory techniques, such as analytical balance operations, pipetting, pH measurement, and reagents preparation.
- Experiences in pharmaceutical production under Good Manufacturing Practice (GMP) are an added advantage.
- Experiences in radiolabelling and purification techniques with short-lived radioisotopes (F-18, C-11, Ga-68) or Lu-177 are highly desirable.
- Proven ability to work independently with minimal supervision as well as a constructive team player.
- Critical thinking and problem-solving skills.
- High attention to detail and commitment to data integrity.
- Ability to perform first-line troubleshooting and minor repairs on automated modules.
- Ability to read technical manuals, interpret wiring diagrams, and communicate effectively with engineers or vendors for equipment servicing.
What We Offer:
Remuneration will be commensurate with the candidate's qualifications and experience. Informal enquiries welcome.
Formal application: Please submit your application, indicating current/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications/oral presentations, and full contacts of three referees) to the NUS Career Portal.
We regret that only shortlisted candidates will be notified.
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