Immunologist, Quantitative Biosciences

Our Research Scientists are our Inventors. We discover and target steps in disease mechanisms or pathways with the goal to identify agents that are effective in treating or preventing human disease. Using innovative thinking, state-of-the-art facilities, and robust scientific methodology we collaborate to discover the next medical breakthrough.

**Key responsibilities**:

- Utilize your background and experience in immunology or immune-oncology research to independently develop and implement potency, selectivity, and mechanistic assays to support compound screening and pharmacological characterization/differentiation using sophisticated experimental methods.
- Work collaboratively in an interdisciplinary team to support research strategies and project goals, critically analyze data and contribute ideas to drive projects forward.
- Lead junior scientists, drive scientific innovation, and champion new enabling technologies to enhance functional capability and productivity.

**Qualifications**:

- PhD in immunology or immune-oncology or in a relevant scientific area with more than 5 years of Postdoctoral experience. Research experienced gained in a biotech or pharmaceutical setting a plus.
- Extensive experience in human immunology or immune-oncology (or in a relevant scientific area), experience in T cell or myeloid cell biology research is strongly preferred.
- Extensive cell culture experience, preferably working with primary human tissue.
- Strong practical experience including isolation, culture, and experimental manipulation of various primary immune cell populations culture and complex flow cytometry systems; willingness to train and lead other research scientists in the design and execution of complex experiments.
- Extensive experience in the execution of immunophenotyping, and a wide range of cellular immunological assays suitable for target identification and functional characterization of biologics and small molecules, including reporter assays, cytokine quantification, receptor target engagement, quantitative PCR (qPCR) and mixed cell assay systems such as PBMC-based functional immune assays (ADCC/ADCP/MLR), preferably within a drug discovery environment.
- Good knowledge of oncology or tumour microenvironments, experience working with complex 3D models would be highly desirable.
- Hands-on experience with advanced imaging techniques would be a plus.
- Solid experimental design, troubleshooting, and data analysis skills.
- Independent, science-based, and innovative thinking, and the ability to mine scientific literature and databases is essential.
- Excellent interpersonal, organizational, and oral/written communication skills with the ability to thrive in a goal-driven team environment.
- Capable of carrying and prioritizing among multiple projects and efficiently advancing projects to meet objectives and milestones.
- Experience mentoring and scientific supervision of junior staff.
- Evidence of productive and impactful scientific contributions measured as first or senior author publications in peer-reviewed journals.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

**Who we are**

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

**What we look for**

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

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**Employee Status**:
Regular
**Relocation**:
Domestic
**VISA Sponsorship**:
**Travel Requirements**:
**Flexible Work Arrangements**:
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