Molecular Biologist, Quantitative Biosciences

2 weeks ago


Singapore MSD Full time

Our Research Scientists are our Inventors. We discover and target steps in disease mechanisms or pathways with the goal to identify agents that are effective in treating or preventing human disease. Using innovative thinking, state-of-the-art facilities, and robust scientific methodology we collaborate to discover the next medical breakthrough.

**Key responsibilities**:

- Utilize your background and experience in molecular biology and cell-based assay development to design and implement novel screening assays and strategies to aid in the design, selection and optimization of nucleic acid sequences to support early drug discovery programs, particularly around RNA therapeutics.- Develop tools and reagents using state of the art technologies such as gene editing to advance drug discovery programs, including the support of validation strategies for target-based, phenotypic, or mechanistic projects.
- Develop, adapt, and implement new research techniques and validate protocols for new assays, enabling their integration into standard workflows.
- Work as part of an interdisciplinary team to support research strategies and project goals, critically analyze data and contribute ideas that will drive projects forward.**Qualifications**:

- PhD in Molecular Biology or Life Science-related discipline or BSc/MSc with more than five years’ significant relevant independent research experience and proven track record of independent scientific achievement.
- Expertise in sequence design, selection, optimization, plasmid generation, in vitro transcription/purification/in vitro transfection, cellular expression, and delivery methods. Advanced bioinformatics a plus.- Expertise in the design, development, and execution of quantitative cell assays, using a wide range of modern technologies and detection methods.
- Strong track record in assay development, optimization and troubleshooting as well as data analysis.
- Extensive knowledge and experience in state-of-the-art technologies such as fluorescent
- or luminescent-based techniques, flow cytometry, fluorescence-activated cell sorting (FACs), and high-content confocal imaging. Experience with advanced lab automation and liquid handlers is a plus.
- Demonstrated experience in methodologies supporting target identification or validation, mechanism of action studies or hit-to-lead-finding activities.
- Solid experimental design, troubleshooting and data analysis skills.
- Excellent interpersonal, organizational, and oral/written communication skills with ability to thrive in a goal driven team environment.
- Comfortable working in a matrix environment and handling several concurrent fast paced projects.
- A proven track record of high productivity and scientific publications in peer reviewed journals.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

**Who we are**

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

**What we look for**

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

**Search Firm Representatives Please Read Carefully**

**Employee Status**:
Regular**Relocation**:
Domestic**VISA Sponsorship**:
**Travel Requirements**:
**Flexible Work Arrangements**:
**Shift**:
**Valid Driving License**:
**Hazardous Material(s)**:
**Requisition ID**:R169397


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