Cell Biologist, Quantitative Biosciences

Our Research Scientists are our Inventors. We discover and target steps in disease mechanisms or pathways with the goal to identify agents that are effective in treating or preventing human disease. Using innovative thinking, state-of-the-art facilities, and robust scientific methodology we collaborate to discover the next medical breakthrough.

**Key responsibilities**:
- Utilize your background and experience in cell biology to perform tissue culture with established cell lines and primary cultures, including organotypic cultures.
- Develop, adapt, and implement new research techniques and validate protocols for new assays, enabling their integration into standard workflows.
- Work as part of an interdisciplinary team to support research strategies and project goals, critically analyzing data and contribute ideas that will drive projects forward.**Qualifications**:

- PhD in cell biology, mechanobiology, pharmacology, bioengineering or equivalent, together with 2-3 years of post-doctoral experience; or an M.S. degree with a minimum of 6 years of relevant experience; or a B.Sc./B.A. degree with a minimum 10 years of relevant experience.
- Highly skilled in the design, development, and execution of quantitative high-complexity cell assays, using a wide range of modern technologies and detection methods.
- Broad expertise in bioassay development and implementation to evaluate compound affinity and potency and assess the molecular mechanisms of action of key compounds.
- Strong track record in assay development, optimization, and troubleshooting as well as pharmacological data analysis.- Knowledge of cancer-associated fibroblast and endothelial biology to elucidate stromal contributions to tumor progression and drug resistance, and/or a strong understanding of oncology concepts at the intersection of stromal, cancer, and immune-oncology are highly desired.
- Demonstrable technical expertise in histology (i.e. immunohistochemistry (IHC), tissue sectioning, in-situ hybridisation), light and fluorescence microscopy, advanced confocal, and wide-field microscopy.
- Experience with high-content assay development and miniaturization, as well as familiarity with correlative imaging and image analysis techniques is highly desirable.
- Demonstrable 3D tissue modeling experience (e.g. spheroids, organoids, hydrogels, bio-scaffolds, organ-on-a-chip/microfluidics, or bioprinting-based tissue models) is a plus.
- Solid experimental design, troubleshooting, and data analysis skills.
- Excellent interpersonal, organizational, and oral/written communication skills with the ability to thrive in a goal-driven team environment.
- Comfortable working in a matrix environment and handling several concurrent fast-paced projects.
- A proven track record of high productivity and scientific publications in peer-reviewed journals.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization.

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

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**Employee Status**:
Regular**Relocation**:
Domestic**VISA Sponsorship**:
**Travel Requirements**:
**Flexible Work Arrangements**:
**Shift**:
**Valid Driving License**:
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**Requisition ID**:R169394