Intern - Exploratory and Enabling Sciences

2 days ago

Singapore MSD Full time

**Job Title: Research Intern, Quantitative Biosciences Singapore**

In Singapore, our research centre focuses on identifying and validating new drug targets, exploring innovative therapeutic modalities, and leveraging clinical studies and patient-derived material to understand biomarkers of disease or therapeutic response, increasing our understanding of human biology and driving our therapeutic pipeline to address unmet medical needs. Our state-of-the-art laboratory supports discovery biology and translational medicine and is an integral part of our Company's world-class network for drug and vaccine discovery. The department's mission is to identify and validate novel targets across various therapeutic areas with multiple discovery biology units.

**What You Will Do**:
As an intern within our research laboratories, you will gain the opportunity to work with talented and dedicated scientists, learn from leading industry experts, gain exposure and professional experience working for a research-driven enterprise; and use your passion, creativity, knowledge and collaboration skills to find solutions to challenging problems in your day-to-day work.
- Gain hands-on experience in different molecular biology, cell biology and high-throughput screening techniques.
- Develop deeper understanding of steps involved in assay development for drug discovery.
- Deep dive into RNA biology and optimization of mRNA therapeutics
- Develop scientific thinking and communication skills through scientific writing and presentations.
- Design, synthesize and test mRNA constructs for their ability to drive cancer cell-specific apoptosis
- Maintain in vitro 2D cell cultures and perform cell-based assays.
- Perform data analysis and develop methods to quantify mRNA half-lives.
- Document relevant experiments and results in electronic notebooks
- Participate, communicate, and present research results in internal scientific discussions between cross-functional teams

**Qualification**:
Enrolment in an Undergraduate or Master’s program leading to a Degree in a Biomedical Sciences, Biological Sciences or Life Sciences-related discipline. Other programs can be considered on individual merit.

**Preferred Experience and Skills**:

- Working knowledge of laboratory-based methodologies such as aseptic cell culture, molecular biology, imaging, and quantitative plate-based detection techniques.
- Hands-on laboratory experience preferred.
- Ability to work with mínimal supervision.
- Strong written and oral communication skills

**Who We Look For**:

- Strong interest in working in a research-intensive environment.
- Excellent communication and facilitation skills
- Interpersonal skills necessary for working in a highly collaborative, cross-functional environment.
- A positive, proactive, can-do attitude
- Strong problem-solving skills
- Availability for 6 months in a full-time capacity preferred

**References**

Jain, Ruchi, et al. "MicroRNAs enable mRNA therapeutics to selectively program cancer cells to self-destruct." _Nucleic acid therapeutics_ 28.5 (2018): 285-296.

**Search Firm Representatives Please Read Carefully**

**Employee Status**:
Intern/Co-op (Fixed Term)

**Relocation**:
**VISA Sponsorship**:
**Travel Requirements**:
**Flexible Work Arrangements**:
**Shift**:
**Valid Driving License**:
**Hazardous Material(s)**:
**Requisition ID**:R280895

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