Application Staff Scientist
2 weeks ago
**Summary**
We are looking for an established bioprocess scientist to lead process development in Singapore **Bioprocess Design Centre **(BDC), as part of an exciting growing network of BDCs in Asia Pacific region for Thermo Fisher Scientific’s cutting-edge bioprocess solutions. Be an integral part of a dynamic high-performing organization with a strong collaborative culture that bridges across regions and business units.
**Responsibilities**:
- Facilitate Singapore BDC capability enhancements for media screening/optimization, upstream and downstream process development and scale-up for biologics and vaccines workflows (including mRNA vaccines)
- Technical project lead and/or expert to design and execute experimental plans. Advises or performs data analysis and technical report generation
- Evaluate new methods and innovative technologies, maintains accurate lab records to support IP protection in accordance with relevant Thermo Fisher required standards
- Develop materials for both internal and external presentations such as project update meetings, customer visits, scientific conferences
- Develop Work Instructions and maintains/calibrates critical lab equipment. Complies with all company safety, training, and quality standards (e.g., ISO compliance, GLP requirements)
- Prepare bills of materials for the service projects and ensure appropriate logístical and shipping support
- Support prioritized pre-sales activities (e.g. customer visits, seminars, conferences, etc.), working with Technical Sales Specialists and Marketing as the technical expert on workflow solutions
- Support BDC training courses as classroom and lab trainer
- Network with colleagues from other BDCs and R&D sites to build effective shared technical resources
- Stays updated with current scientific literature, and shares knowledge of latest competing technologies and products
- Contribute to Thermo Fisher regional SME (Subject matter expert) and SPOG (Single point of contact) networks
- Participate actively in external technical conferences and industry body forums
**Qualifications / Experience**:
- Masters' degree in Life Sciences (Biochemistry, Biotechnology, Engineering, Virology). PhD degree preferred
- 10+ years’ hands-on experience in upstream and downstream R&D, process development, MSAT. Direct experience in statistical experimental design (DoE), mRNA/vaccine production workflows is highly preferred
- 5+ years’ experience in developing upstream processes at bench and pilot scales (including fed-batch and perfusion). Experience in viral vaccine production/virus production in roller bottles, stacked plate systems, micro-carriers, or other similar systems is a plus
- 3+ years’ microbial fermentation experience using E.coli, Pichia etc from bench scale to pilot-scale, preferably with single-use fermentors
- 3+ years’ experience in downstream processes development and scale-up. Experience packing of pilot-manufacturing scale chromatography columns is highly preferred
**Additional Desirable Skillsets/Experience**:
- Program/project management experience
- Team management experience
- Managing external scientific collaborations, CRO or CDMO
- Proven fast learner on new technology / knowledge / process
- Excellent verbal and written scientific communication skills.
- Excellent organizational skills, including the ability to efficiently evaluate and manage multiple projects and tasks
**Working Conditions**:
- Able to work flexible hours
- Able to undertake up to 30% overseas travel for training and customer engagements
- Work in a GLP laboratory environment, handle approved chemicals and hazardous materials safely
Visit our Career Site and join our Talent Community for exciting career opportunities within Thermo Fisher.
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