Application Staff Scientist
6 days ago
We are looking for an established bioprocess scientist to lead process development in Singapore BDC, as part of an exciting growing network of BDCs in Asia Pacific region for Thermo Fisher Scientific’s cutting-edge bioprocess solutions Be an integral part of a multifaceted impactful organization with a strong collaborative culture that bridges across regions and business units
**Responsibilities**:
- Facilitates Singapore BDC capability improvements for media screening/optimization, upstream and downstream process development and scale-up for biologics and vaccines workflows (including mRNA vaccines).
- Technical project lead and/or expert to craft and execute experimental plans. Advises or performs data analysis and technical report generation.
- Evaluates new methods and innovative technologies, maintains accurate lab records to support IP protection in accordance with relevant Thermo Fisher required standards.
- Develops materials for both internal and external presentations such as project update meetings, customer visits, scientific conferences.
- Develops Work Instructions and maintains/calibrates critical lab equipment. Complies with all company safety, training, and quality standards (e.g., ISO compliance, GLP requirements).
- Prepares bills of materials for the service projects and ensure appropriate logístical and shipping support.
- Supports prioritized pre-sales activities (e.g. customer visits, seminars, conferences, etc.), working with Technical Sales Specialists and Marketing as the technical expert on workflow solutions.
- Supports BDC training courses as classroom and lab trainer.
- Networks with colleagues from other BDCs and R&D sites to build effective shared technical resources.
- Stays updated with current scientific literature, and shares knowledge of latest contending technologies and products.
- Contributes to Thermo Fisher regional SME (Subject matter expert) and SPOG (Single point of contact) networks.
- Participates actively in external technical conferences and industry body forums.
**Qualifications / Experience**:
- Masters degree in Life Sciences (Biochemistry, Biotechnology, Engineering, Virology). PhD degree preferred.
- 10+ years’ hands-on experience in upstream and downstream R&D, process development, MSAT. Direct experience in statistical experimental design (DoE), mRNA/vaccine production workflows is highly preferred.
- 5+ years’ experience in developing upstream processes at bench and pilot scales (including fed-batch and perfusion). Experience in viral vaccine production/virus production in roller bottles, stacked plate systems, micro-carriers, or other similar systems is a plus.
- 3+ years’ microbial fermentation experience using E.coli, Pichia etc from bench scale to pilot-scale, preferably with single-use fermentors.
**Additional Desirable Skillsets/Experience**
- Downstream processes development and scale-up. Experience packing of pilot-manufacturing scale chromatography column
- Program/project management experience
- Team management experience
- Proven fast learner on new technology / knowledge / process.
- Excellent verbal and written scientific communication skills.
- Excellent interpersonal skills, including the ability to efficiently evaluate and manage multiple projects and tasks.
**Working Conditions**:
- Able to work flexible hours.
- Able to undertake up to 30% overseas travel for training and customer engagements.
- Work in a GLP laboratory environment, handle approved chemicals and materials safely.
- Thermo Fisher Scientific is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, creed, religion, color, national or ethnic origin, citizenship, sex, sexual orientation, gender identity and expression, genetic information, veteran status, age or disability status._
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