Scientist (Computational Chemical Biology and Fragment-based Design), Bii

The Yu Lab (launching in April 2025) at the Genome Institute of Singapore (GIS), A*STAR, is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA- and DNA-targeted drug discovery. Our goal is to re-engineer small molecules and...

About Bioinformatics Institute The Bioinformatics Institute (BII) was set up by the Agency for Science, Technology and Research (A*STAR) in July 2001; it was re-launched with a strong scientific program in 2007. Located in the Biopolis in Singapore, BII is conceived as the computational biology research and postgraduate training institute as well as a...

Job Description Job Requirements Bachelor's degree in life sciences, chemistry, computational biology, or a related discipline Passion for science and research Strong knowledge of structural biology Keen interest in programming. Prior experience is preferred, but not required. Able to work independently and as part of a team Highly motivated Excellent...

The Yu Lab is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA-targeted drug discovery. Our goal is to re-engineer antisense oligonucleotides (ASOs) for gene-selective regulation, paving the way for rational drug...

Job Description **Responsibilities**: - Play a key role in developing comprehensive bioinformatics or computational modelling solutions for enzymatic reactions and metabolic networks - Develop dynamic or machine-learning models that interprets enzymes and metabolites data - Analyse experimental datasets using modeling and machine learning approaches, and...

Our group A part-time position is available at the Protein Sequence Analysis Group in Bioinformatics Institute, A*STAR. In this global fight against Covid-19, our group is collaborating closely with multiple local and international partners. The following are some of the work we do in the group (i) development of the CoVsurver tool which we developed to...

**Principle Roles & Responsibilities**: Lead and design preclinical research programs focused on identifying and validating novel therapeutic targets in immunology. Develop and optimize cell-based assays, flow cytometry panels, and molecular biology techniques to support drug discovery. Participate in the evaluation of internal as well as external...

EDDC is a drug discovery organization committed to work with the SG ecosystem to translate scientific discoveries into life-changing therapeutics for patients. We aim to leverage state-of-the-art computational and data-driven approaches to uncover insights from large-scale and multidimensional data sources, and to tackle complex and unmet medical challenges...

**Principle Roles & Responsibilities**: Design and execute experiments involving cancer cell lines, primary human (PBMCs) and mouse immune cells in co-culture assays with mínimal supervision. Prepare standard operating procedures and document study reports. Provide technical support for certain experimental procedures and serve as point of contact for the...

A*STAR Centre for Frontier AI Research (CFAR) Singapore is seeking an exceptional Computer Vision/Machine Learning Scientist to expand our dynamic and multi-disciplinary AI team. We are looking for two-research scientists with a background in Computer Vision and Machine learning to work on human action understanding using neurosymbolic AI approaches....