Senior Scientist, Eddc
2 weeks ago
**Principle Roles & Responsibilities**: Lead and design preclinical research programs focused on identifying and validating novel therapeutic targets in immunology. Develop and optimize cell-based assays, flow cytometry panels, and molecular biology techniques to support drug discovery. Participate in the evaluation of internal as well as external collaborative projects. Analyze, interpret, and present complex data to internal stakeholders and external partners. Stay up to date with relevant scientific literature, research on translatability of preclinical disease models and novel mechanisms of action of particular importance within the I&I therapeutic space. Collaborate with cross-functional teams including medicinal chemistry, antibody technology, in vivo pharmacology, computational biology and clinical development. Mentor and train junior scientists, providing technical guidance, fostering scientific development, and supporting career growth within the team. **Requirements**: Ph.D. in Immunology, Cell Biology, Molecular Biology, or related field with > 8 years working experience and mínimally 3 years experience in the industry sector. Strong expertise in immune cell biology, cytokine signalling, and autoimmune disease models. Experience with primary human PBMCs, along with a strong understanding of tissue repair and regeneration in the context of immune resolution. Proven expertise in developing and optimizing cell-based functional assays. Excellent communication and presentation skills, with the ability to clearly convey scientific concepts and influence stakeholders across multidisciplinary teams. Proven track record of scientific innovation, publications, and project leadership. Ability to work independently and collaboratively in a fast-paced, dynamic environment. Experience with biologics or small molecule therapeutics is preferred. Familiarity with bioinformatics tools and multi-omics data analysis is preferred. **Type of Employment**: Full-Time **Minimum Experience**: 8 Years **Work Location**: Biopolis
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Data Engineer
1 week ago
Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full timeEDDC is a drug discovery organization committed to work with the SG ecosystem to translate scientific discoveries into life-changing therapeutics for patients. We aim to leverage state-of-the-art computational and data-driven approaches to uncover insights from large-scale and multidimensional data sources, and to tackle complex and unmet medical challenges...
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Manager (Business Development and Alliance
2 weeks ago
Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full timeThe Innovation & Enterprise Fellowship Programme (IFP) seeks to grow a pool of deep-tech talent in Singapore with capabilities to support the commercialisation of deep-tech research and bring nascent technologies to market. Targeting researchers, scientists and engineers (RSEs), the IFP programme aims to develop industry relevant innovation and...
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Research Fellow
2 weeks ago
Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full timeThe Innovation & Enterprise Fellowship Programme (IFP) seeks to grow the pool of deep-tech talent in Singapore with the capabilities to support the commercialisation of deep-tech research and bring nascent technologies to market. Targeting researchers, scientists, and engineers (RSEs), the programme aims to develop industry relevant innovation and...
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(Senior) Research Associate
2 weeks ago
Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full time**Principle Roles & Responsibilities**: Design and execute experiments involving cancer cell lines, primary human (PBMCs) and mouse immune cells in co-culture assays with mínimal supervision. Prepare standard operating procedures and document study reports. Provide technical support for certain experimental procedures and serve as point of contact for the...
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Junior Scientist, Eddc
3 days ago
Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full time**Principal roles and responsibilities**: Develop and perform mammalian cell culture, biochemical, biophysical and cellular assays such as Western blotting, flow cytometry, thermal shift assays, plate-based assays involving fluorescence or luminescence for target validation and functional characterization of small and large molecule therapeutics. Support...
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Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full timeThe Yu Lab (launching in April 2025) at the Genome Institute of Singapore (GIS), A*STAR, is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA- and DNA-targeted drug discovery. Our goal is to re-engineer small molecules and...
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Scientist, Cfar, Ihpc
2 days ago
Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full timeAt A*STAR, we make it our mission to attract and develop a diversity of talent along the research, innovation, and enterprise value chain, with career paths developed for scientists, engineers, and entrepreneurs. In return, we commit to investing in the personal and professional growth of each of our officers. CFAR has a team of exemplary AI researchers...
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Senior Scientist, Cfar, Ihpc
2 days ago
Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full timeAt A*STAR, we make it our mission to attract and develop a diversity of talent along the research, innovation, and enterprise value chain, with career paths developed for scientists, engineers, and entrepreneurs. In return, we commit to investing in the personal and professional growth of each of our officers. CFAR has a team of exemplary AI researchers...
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Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full timeThe research scientist will be working with a team to carry out basic research in trustworthy formal methods. The topics of interest under this project include trustworthy automated reasoning, verification of randomized algorithms, compiler verification, and control/hybrid systems verification. KEY RESPONSIBILITIES **Research and Development**: To carry out...
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Buona Vista, Singapore A*STAR Agency for Science, Technology and Research Full timeBe able to work as a lead scientist for the development of purification process and analytics for the production of a variety of emerging biotherapeutics, such as bispecific and multi-specific antibodies, vaccines, viral vectors and nucleic acid therapies. - Be able to lead a few research officers to work on different industrial collaboration projects and...