Research Officer, Computational Chemical Biology

The Yu Lab is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA-targeted drug discovery. Our goal is to re-engineer antisense oligonucleotides (ASOs) for gene-selective regulation, paving the way for rational drug...

About Bioinformatics Institute The Bioinformatics Institute (BII) was set up by the Agency for Science, Technology and Research (A*STAR) in July 2001; it was re-launched with a strong scientific program in 2007. Located in the Biopolis in Singapore, BII is conceived as the computational biology research and postgraduate training institute as well as a...

Job Description **Responsibilities**: - Play a key role in developing comprehensive bioinformatics or computational modelling solutions for enzymatic reactions and metabolic networks - Develop dynamic or machine-learning models that interprets enzymes and metabolites data - Analyse experimental datasets using modeling and machine learning approaches, and...

The Yu Lab (launching in April 2025) at the Genome Institute of Singapore (GIS), A*STAR, is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA- and DNA-targeted drug discovery. Our goal is to re-engineer small molecules and...

**Key Responsibilities**: Develop and implement AI-driven models for ligand discovery, with a focus on generative models. Collaborate closely with multidisciplinary teams to integrate computational methods with experimental research. Stay abreast of the latest developments in AI and molecular modelling. Communicate research findings effectively, both in...

Our group A part-time position is available at the Protein Sequence Analysis Group in Bioinformatics Institute, A*STAR. In this global fight against Covid-19, our group is collaborating closely with multiple local and international partners. The following are some of the work we do in the group (i) development of the CoVsurver tool which we developed to...

**Requirements**: - Bachelor?s or Master?s degree in Bioinformatics, Computational Biology, Data Science, or a related field - High proficiency in scripting language (Perl, Python and statistical languages such as R, particularly in the use of packages such as Bioconducter or Biopython) - A strong background and course work in statistics, computer science...

The Innovation & Enterprise Fellowship Programme (IFP) seeks to grow the pool of deep-tech talent in Singapore with the capabilities to support the commercialisation of deep-tech research and bring nascent technologies to market. Targeting researchers, scientists, and engineers (RSEs), the programme aims to develop industry relevant innovation and...

**Principle Roles & Responsibilities**: Design and execute experiments involving cancer cell lines, primary human (PBMCs) and mouse immune cells in co-culture assays with mínimal supervision. Prepare standard operating procedures and document study reports. Provide technical support for certain experimental procedures and serve as point of contact for the...

Intra-operative imaging is an ambitious translational effort that brings together the brightest minds from engineering, microscopy, and biomedicine. Join a new initiative at the Institute of Bioengineering and Bioimaging, A*STAR to develop cutting edge optical imaging technologies for rapid tissue diagnostics. The Research Officer will work with the...