Scientist, Analytics and Mass Spectrometry

3 days ago


Singapore Hummingbird Bioscience Pte. Ltd Full time

**ABOUT HUMMINGBIRD BIOSCIENCE**

Hummingbird Bioscience is a data-driven precision biotherapeutics team discovering and developing transformative biologic medicines for hard-to-treat diseases. The Hummingbird Bioscience model combines computational and systems biology and wet lab drug discovery in a multi-disciplinary, collaborative environment spanning initial discovery through clinical development. We harness this integrated approach across target identification and patient selection, enabling our team to increase the efficiency of translating novel scientific insights while reducing the inherent risk in drug discovery and development. At Hummingbird Bioscience, our commitment to rigorous science, teamwork, and intellectual integrity underpins our passion to accelerate the journey of new drugs from concept to clinic.

**ABOUT THE ROLE**

**KEY RESPONSIBILITIES**
- Responsible for development of in-house mass spectrometry assays to support the advancement of novel antibody drug conjugate (ADC) programs
- Design and execute a wide range of LC-MS assays for characterization of ADCs and antibodies (including but not limited to Drug-Antibody Ratio, free drug, intact mass, peptide mapping)
- Perform high quality LC-MS data analysis of ADCs and antibodies to support screening activities for early stage programs
- Provide strong technical expertise and guidance to the team and lead complex troubleshooting activities when required
- Liaise and work effectively with external stakeholders (e.g. CROs/ CDMOs) to ensure deliverables are met in a timely manner by providing input and expertise when required
- Lead initiatives to improve and increase throughput of existing LC-MS workflows
- Effectively communicate and present scientific findings to stakeholders
- Work closely with the team to support implementation of new cutting-edge tools and techniques for ADC and antibody drug discovery and development cycle
- Produce accurate documentation such as reports, presentations, protocols and SOPs to record detailed procedures, data and results and deliver the results within expected timelines
- Perform administrative duties including regular updates, maintenance of lab and equipment, consumables order and inventory to ensure smooth operation in the team
- Contribute to the overall safety and organization of the laboratory

**ESSENTIAL QUALIFICATIONS**
- BSc or higher in Analytical Chemistry, Biochemistry or related field
- At least 7 years of relevant experience in mass spectrometry in a biopharma industry and/or academia
- Strong knowledge or experience in the antibody and/ or ADC field
- In depth experience in method development to support LC-MS analysis for complex biomolecules like ADCs/ antibodies
- Excellent communication (written and verbal) and interpersonal skills
- Able to work both independently and collaborate as an effective team player
- Agility to work in a dynamic fast-paced environment

**ESSENTIAL QUALIFICATIONS**
- Experience withs QTOF and/or Triple Quad and UNIFI software
- Experience in working within a GxP environment
- Experience in working alongside CRO and CDMOs

**OUR MISSION & VALUES**

Our fast-growing biotechnology company is committed to discovering and developing important new drugs for cancer and autoimmune diseases, and living by our values: Excellence, Determination, Teamwork, Intellectual Integrity and Audacity.

**JOIN US AT THE FRONTIER OF DRUG DISCOVERY AND DEVELOPMENT**

We are looking for passionate and motivated individuals committed to solving important, complex problems. We are committed to the personal and professional development of our team and offer robust learning and development programs. Hummingbird Bioscience understands the need for flexibility for our team and offers a generous paid time off program with flexibility to support employees through different life stages. We invest in our team’s health by offering competitive benefits including health and dental insurance, and a comprehensive and holistic employee assistance program. We foster a more collaborative, productive, and sociable culture with on-site lunches and snacks. Finally, we believe in creating social impact beyond our business through corporate social responsibility initiatives.
- Hummingbird Bioscience is firmly committed to Equal Employment Opportunity (EEO) and to compliance with all Singapore and US federal, state and local laws and/or guidelines that prohibit employment discrimination on the basis of age, race, color, gender, sexual orientation, gender identity, ethnicity, national origin, citizenship, religion, genetic carrier status, disability, pregnancy, childbirth or related medical conditions, marital status, protected veteran status and other protected classifications._



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