Senior Research Officer, Immune Cell Manufacturing

7 hours ago


Singapore A*STAR - Agency for Science, Technology and Research Full time

Senior Research Officer, Immune Cell Manufacturing (BTI)Join to apply for the Senior Research Officer, Immune Cell Manufacturing (BTI) role at A*STAR – Agency for Science, Technology and Research. Job description We are looking for a highly motivated candidate to join the immune cell manufacturing group at the Bioprocessing Technology Institute (BTI). Regulatory T cells (Tregs) are a key player in immune tolerance and their use as a cell‐therapy treatment for autoimmune disease or organ transplant has been growing globally. This project will contribute towards developing a CAR‐Treg manufacturing and quality control (QC) pipeline for transplant tolerance in Singapore. Our team will use cell engineering strategies to improve the purity and efficacy of our manufactured Tregs, optimizing for clinical success. Wet lab Isolation, transduction, and expansion of PBMC‐derived Tregs to support process development work. Perform molecular and immunological assays to assess the quality and specificity of Tregs. Record experimental findings and present analysis results. This role will occasionally require work beyond regular hours and on weekends during crucial timepoints. Lab management Handling of lab inventory and procurement of equipment and consumables. Facilitate laboratory maintenance, safety, and housekeeping of lab and equipment. Requirements Bachelor degree in Biology, Immunological Sciences, Biomedical Engineering, Biotechnology or relevant disciplines. Key skills and areas of experience required: Flow Cytometry, PBMC isolation, Immune Cell Culture, Lab management experience (2 years minimum). Highly motivated and able to work independently after training. Team player with good interpersonal skills to communicate and work well with group members and collaborators. Seniority level Associate Employment type Full‐time Job function Research, Analyst, and Information Technology Industries Research Services #J-18808-Ljbffr



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