Purification Development Lead

1 month ago


Singapore Lonza Full time
About Lonza

Lonza is a global leader in life sciences operating across three continents, dedicated to delivering innovative solutions that improve lives worldwide. Our success is built on the foundation of talented individuals working together to devise ideas that drive business growth and help people.

We empower our employees to own their careers, fostering an environment where big and small ideas genuinely make a difference. As part of our team, you'll be part of a dynamic network recognized for its reliable high-quality services, regulatory track record, global footprint, and innovative technology platforms.

Job Title: Purification Development Lead - Innovation Driven Scientist

As a key member of our Purification Development team, you will lead multiple projects in protein purification process development, overseeing junior scientists and contributing to the development of processes suitable for technology transfer to cGMP manufacturing teams.

You will be responsible for efficient planning and prioritization of lab work, hands-on experimental activities, project leadership, and coordination with cross-functional teams. Your expertise in purification processes, including Chromatography (Affinity, Mixed-mode, ion exchange) using AKTA systems, Ultrafiltration/diafiltration, and viral reduction strategies, will drive innovation in the field.

Responsibilities:
  • Purification process development, including protein purification of monoclonal antibodies, fusion proteins, bispecifics, and complex proteins.
  • Process Characterization activities, including Risk Assessment, employing DoE methodologies, data analysis, and interpretation to define process parameter ranges and steps.
  • Drafting and reviewing high-quality technical documents, such as protocols, reports, SOPs, and ensuring results are documented in accordance with Lonza policies and current Good Manufacturing Practices (cGMP).
  • Effective communication and delivery of high-quality customer experiences through written documents, telecons, and face-to-face meetings.
  • Contributing to operational efficiency initiatives, general lab support, and troubleshooting equipment and scientific issues.
Requirements:
  • Degree/PhD in a relevant Science field or equivalent.
  • Minimum 5 years' work experience in a relevant field or PhD with 2 years postdoctoral/3 years of industrial experience.
  • Expertise in protein purification process development, preferably with experience in Process Characterization/Validation involving statistical software for experimental design and data analysis.
  • Understanding of cGMP regulations and excellent technical writing skills.
  • Excellent communication, problem-solving, analytical, and team-working skills.
Salary Estimate: $120,000 - $180,000 per year

Please note that the salary estimate provided is based on industry standards and may vary depending on individual qualifications, location, and other factors. We offer competitive compensation packages that reflect the value we place on our employees' contributions.



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