Advanced Microprotein Researcher

5 days ago

Singapore beBeeBiologist Full time $100,000 - $140,000
Computational Biologist Opportunity

We seek a highly skilled computational biologist to join our cutting-edge research program at the forefront of proteogenomics and artificial intelligence.

Our lab is dedicated to discovering novel microproteins encoded by the dark proteome, which have been found to be critical regulators of fundamental biological processes.

As a member of our team, you will play a key role in developing and implementing innovative computational pipelines integrating ribosome profiling (Ribo-seq), transcriptomics, and metabolomics data.

  • Key Responsibilities:
  • Develop and implement computational pipelines for integrating multi-omics data
  • Apply and enhance existing smORF identification tools and develop novel AI-driven approaches for predicting microprotein function
  • Lead computational analysis of multi-omics datasets to prioritize disease-relevant microprotein candidates
  • Design prediction models to identify microproteins involved in metabolism, inflammation, and heart disease
  • Collaborate with wet-lab scientists to validate computational predictions and refine prediction models
  • Contribute to the development of new algorithms for improved microprotein detection and functional annotation
  • Participate in commercialization activities and innovation development
  • Present findings at international conferences and prepare manuscripts for high-impact publications

Requirements:

  • Ph.D. in Bioinformatics, Computational Biology, Computer Science, or related field
  • Strong programming skills in Python, R, or similar languages
  • Experience with next-generation sequencing data analysis, particularly Ribo-seq
  • Proficiency in statistical analysis and machine learning methods
  • Demonstrated ability to develop and maintain computational pipelines
  • Strong publication record in computational biology or related fields

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