Genomics Expert

7 days ago

Singapore beBeeGenomics Full time $90,000 - $120,000
At Lucence, we are a pioneering precision oncology company with a bold vision: a world where cancer is defeated through early detection and timely treatment. Our cutting-edge liquid biopsy tests use advanced molecular profiling to guide personalized cancer therapies, transforming how cancer is diagnosed and treated.We are shaping the future of precision medicine by capturing both genetic and cellular data from a single blood draw, bringing us closer to our mission of overcoming cancer.Key Responsibilities:
  • Drive development and automation of novel next-generation sequencing workflows or genomic medicine technologies.
  • Propose, design, plan, execute, and interpret laboratory experiments to implement new molecular assays and improve current assays.
  • Design, plan, and lead studies for analytical and clinical verification and validation.
  • Author, review, and maintain internal workflows and protocols of validated molecular diagnostics assays.
  • Analyse genomic data and publish/present work in peer-reviewed journals and international conferences.
  • Collaborate closely with top-tier scientists, doctors, bioinformaticians and software engineers to develop new technologies and/or assays.
You would be a good fit for this role if you have:
  • A PhD in Molecular Biology, Cancer Biology, Genomics, or related field.
  • A proven track record of quick learning.
  • Strong background in molecular biology, including PCR, RT-PCR, genotyping and NGS.
  • At least 1 years of working experience in the development of molecular assays, with significant hands-on expertise in troubleshooting, implementing, and optimising assays.
Additional requirements include:
  • Strong self-motivation, resilience, adaptability, and a keen interest in learning.
  • Excellent communication and presentation skills.
The following qualifications would be advantageous:
  • A deep understanding and knowledge of oncology and/or genomics.
  • Proficiency in R or Python.
  • Experience in validation of NGS assays in a CLIA-compliant manner.
  • Fluency in variant annotation and interpretation and use of genome databases such as COSMIC, ClinVar, Varsome, Ensembl, and OncoKB.
  • Ability to interpret genomic data in patient- and treatment-specific contexts.
  • Good track record of publications.

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