Lab Technologist

2 months ago

Singapur, Singapore GenScript Full time

About GenScript

GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.

GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology

About ProBio

ProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio's total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. In terms of plasmid service, ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China. It is also the first GMP manufacturing platform to provide in vitro transcription (IVT) template linearized plasmids for mRNA vaccines and has supported several mRNA vaccine global enterprises to obtain clinical approvals. In terms of viral vector service, \ProBio has a stable and high-yield viral vector platform.

What you will be doing:

  • Performing a wide range of technical and analytical tasks in our state-of-the-art laboratory
  • Perform cell culture experiments, data analysis and documentation of the results
  • Maintaining and troubleshooting laboratory equipment to ensure optimal performance
  • Documenting procedures, protocols, and findings in a detailed and organized manner
  • Collaborating with cross-functional teams to identify and resolve technical challenges
  • Ensuring strict adherence to all laboratory safety protocols and procedures

Protein Expression

  • Responsible for resuscitation, passage, transfection, culture and other experiments of mammalian cells such as HEK293 and CHO
  • Perform cell culture experiments, data analysis and documentation of the results
  • Operate bioreactors, centrifuges and prepare buffers and reagents

Protein Purification

  • Purification of mammalian recombinant antibody and protein by affinity chromatography, ion exchange chromatography, size exclusion chromatography and other methods
  • Formulate appropriate purification scheme according to order requirements
  • Responsible for filling-in and verifying records related to purification experiment
  • Use Western blotting and SDS-PAGE techniques to assess the quality, quantity, and identity of the purified proteins

What we are looking for:

  • Bachelor's Degree in a relevant scientific discipline, such as life sciences, biological chemistry etc
  • Some familiarity in the use of various laboratory equipment and instrumentation
  • Good technical and problem-solving skills
  • Excellent attention to detail and a commitment to accurate and precise work
  • Excellent communication and interpersonal skills, with the ability to work collaboratively
  • Available to work 8-hour shifts, 5 days a week, with 2 rest days that may not always fall on weekends

GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.

GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.

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