Scientist, Laboratory of Regulatory Translatomics and Rna Signaling

The HWJ lab seeks a laboratory officer to join our group at IMCB, A*STAR, Singapore. The successful applicant will work under a highly experienced Research Scientist to understand precise genetic mechanisms underlying cancer cell signalling between different cell types in 2D and 3D models. Our group develops and applies novel 2D and 3D cellular assays to...

The Yu Lab (launching in April 2025) at the Genome Institute of Singapore (GIS), A*STAR, is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA- and DNA-targeted drug discovery. Our goal is to re-engineer small molecules and...

**Job requirements**: PhD with experience in molecular biology and bioinformatics **Job duties & responsibilities**: Perform computational analysis to study RNA secondary andtertiary structures using Illumina and nanopore sequencing.

**Key Responsibilities**: Design and execute experiments to investigate gene expression in single cells and spatially resolved tissue samples Analyze data from transcriptomic and genomic assays including single cell RNAseq, spatial transcriptomics, and other sequencing technologies Develop and optimize experimental protocols for large scale single cell...

**JOB DESCRIPTION**: We are looking for a research personnel who is highly motivated, passionate for science, committed to laboratory ethics and can work flexible hours. The person will be involved in an ongoing IMCB project on ‘Novel differentiating stem cell-based therapeutic approaches to chronic wound infection’. Job scope includes 1. Perform wet...

Research Officer (NHH lab), GIS The Laboratory of Precision Disease Therapeutics at the Genome Institute of Singapore is currently recruiting a Research Officer to engage in research at the forefront of stem cells and liver biology. Research Area Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease of global concern, affecting over a quarter...

**Job description**: Assist Senior Scientist in conducting research activities for developing microneedle-based mRNA carriers Perform microneedle sample preparation and characterization Conduct RT-qPCR and Western blot experiments to confirm target mRNA translation Assist in cell and animal experiments as necessary Record experimental findings and present...

**Background**: GAD at GIS has been focusing on genomics of non-human organisms including plant, bacteria, fungi, etc. The works include genome assembly, gene annotation and expression but to date we lack experts in functional genomics for these organisms that can further translate our genomic works via gene-editing (eg., CRISPR) and other forms of...

We invite brilliant minds in computer science to join us at the cutting-edge of cancer genomics research, harnessing the power of artificial intelligence or classical algorithms. Your job will involve either the development of new algorithms or deep learning models focusing on understanding cancer genomes. The focus will be on de novo genome assembly methods...

The Yu Lab is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA-targeted drug discovery. Our goal is to re-engineer antisense oligonucleotides (ASOs) for gene-selective regulation, paving the way for rational drug...