Scientist, Laboratory of Regulatory Genomics

We invite brilliant minds in computer science to join us at the cutting-edge of cancer genomics research, harnessing the power of artificial intelligence or classical algorithms. Your job will involve either the development of new algorithms or deep learning models focusing on understanding cancer genomes. The focus will be on de novo genome assembly methods...

A*STAR Genome Institute of Singapore (A*STAR GIS) is seeking a Research Assistant to join us in our mission to be a leading centre of precision medicine. As an Assistant Lab Officer within our research laboratories, you will gain the opportunity to work with talented and dedicated scientists, learn from leading research experts, gain exposure and...

The Yu Lab (launching in April 2025) at the Genome Institute of Singapore (GIS), A*STAR, is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA- and DNA-targeted drug discovery. Our goal is to re-engineer small molecules and...

We invite brilliant minds in computer science to join us at the cutting-edge of cancer genomics research, harnessing the power of artificial intelligence or classical algorithms. Your job will involve either the development of new algorithms or deep learning models focusing on understanding cancer genomes. The focus will be on de novo genome assembly methods...

**Background**: GAD at GIS has been focusing on genomics of non-human organisms including plant, bacteria, fungi, etc. The works include genome assembly, gene annotation and expression but to date we lack experts in functional genomics for these organisms that can further translate our genomic works via gene-editing (eg., CRISPR) and other forms of...

Research Officer (NHH lab), GIS The Laboratory of Precision Disease Therapeutics at the Genome Institute of Singapore is currently recruiting a Research Officer to engage in research at the forefront of stem cells and liver biology. Research Area Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease of global concern, affecting over a quarter...

The Yu Lab is a chemical biology lab dedicated to translational research targeting cellular nucleic acids. We integrate functional genomics, chemical biology, and molecular pharmacology to advance RNA-targeted drug discovery. Our goal is to re-engineer antisense oligonucleotides (ASOs) for gene-selective regulation, paving the way for rational drug...

The lab is seeking motivated postdoctoral Fellows to study 3 projects: - Ribosome and translation mechanisms changes in the tumour microenvironment - CircRNA functional analysis in cells and extracellular vesicles in refractory cancers - RNA therapeutic development Key Requirements PhD degree in Life Sciences, Genomics, Molecular Biology, or a related...

Positions for Postdoctoral Fellows in Laboratory of Translational Cancer Biology The Laboratory of Translational Cancer Biology at the Genome Institute of Singapore is currently recruiting Postdoctoral Fellows. Postdoctoral Fellows **Project 1**: Dissecting the metabolic control of cancer cell states **Project 2**: Exploiting the biophysical properties...

**In this position, you are required to be**: Proficient in working with liver stem cell lines and primary cell cultures, including genetic manipulation in culture systems. Familiar with mouse models, particularly related to liver biology. Analyse and integrate multi-omics datasets. Assist in the design, planning, and execution of research projects. Collect,...