Head of Precision Medicine Asia

**Site Name**: Singapore - Rochester Park
**Posted Date**: Dec 12 2024

Precision Medicine is an organization within Development which aims to drive end-to-end clinical development of innovative medicines and vaccines with clinical pharmacology, model-informed drug and vaccine development, biomarker and diagnostic strategies, state-of-the-art bioanalysis capabilities, to transform clinical care and drive meaningful patient outcomes. Through this we inform the clinical development of the right medicine or vaccine at the right dose (regimen) at the right time for the right patient supported with the right assays.

Does this mission excite you? If so, GSK Asia Development is evolving to address specific demands and growth opportunities in Asia, especially in China and Japan, by focusing on both regional challenges and potential to strengthen GSK’s influence. The strategy centres on three priorities:

- Execution: Accelerate delivery of Innovative Medicines and Vaccines in Asia, by impactful contribution to co-creation of strategy and execution, actively shaping the ecosystem in China and Japan.
- Technology: Drive innovation and tech advancements in Asia and beyond, by enabling business development and harnessing cutting-edge digital tools and tech
- Culture: Foster culture of inclusivity and collaboration and nurture both Asian and next-gen global leaders to ensure they thrive

**What we are looking for**

**Key responsibilities**:
**Strategic Leadership**:

- Represents Precision Medicine organization on the Asia development leadership team and ensures full integration of the Precision Medicine strategy within the overall Asia development plans.
- Develop and implement Precision Medicine strategies specific to the Asian population while aligning with the global objectives.
- Lead clinical pharmacology and bioanalytical operational and regulatory strategies with respect to Chinese and Japanese authorities with a vision to expand to other countries in the region
- Identify opportunities to integrate clinical pharmacology, MIDD, and biomarker and diagnostic capabilities into Asia development efforts to personalise treatments for the Asian population.
- Ensures unified vision, strategy, goals, ways of working and communications across regional and global Precision Medicine teams.
- Approval of design, analysis, interpretation, reporting and corresponding regulatory documents across a portfolio of programs

**Team Management and Development**:

- Lead and manage a multidisciplinary team specialising in clinical pharmacology, biomarkers, bioanalytical, and diagnostic capabilities.
- Foster a high-performing, collaborative team environment, driving innovation and professional growth.
- Contribute to group's awareness of the emerging regional and global key scientific and technical innovations to help drive our continuous improvement.
- Maintain strong working relationships with the global functions within the Precision Medicine organization and with the regional cross-functional Asia development team.

**Clinical Pharmacology Expertise**:

- Ensure optimal dose selection and therapeutic strategies through data-driven and model-based approaches.
- In close alignment with global clinical pharmacology strategies, oversee the clinical pharmacology components of all regulatory documents and responses such that GSK products are rapidly and efficiently approved with optimum labelling.
- Work with local and global experts to design and implement optimized MIDD strategies

**Biomarker and Diagnostics Integration**:

- In collaboration with global clinical biomarker team, oversee biomarker discovery, validation, and implementation to support patient selection and monitoring strategies in Asia development.
- Oversee the writing and editing of the relevant biomarker sections of the clinical protocol, study procedural manuals and consent forms.
- Collaborate on the development and integration of diagnostics into clinical development programs.
- Work with local testing partners and health and regulatory authorities to enable development, testing, validation, and registration of diagnostics as needed per the Asia development asset plan.

**Cross-functional Collaboration**:

- Work closely with internal and external stakeholders, including development, biostatistics, regulatory, and commercial teams, to ensure Precision Medicine strategies are effectively executed in Asia.
- Partner with regulatory authorities in Asia to ensure compliance with Precision Medicine requirements.
- Drive partnership sourcing and evaluation by enabling appropriate selection of capable partners to allow tech / innovation capture

**Basic Qualifications**:

- PhD or equivalent in clinical pharmacology, pharmacokinetics, biopharmaceutics, or other relevant discipline
- Minimum of 10 year experience in Clinical Pharmacology in an industry setting with different components of a precision medicine strategy.
- Direct experience with regulatory interactions (e