(Senior) Scientist, Process Sciences

6 days ago

Singapore Tessa Therapeutics Pte Ltd Full time

**Company Background**

Tessa Therapeutics is a clinical-stage biotechnology company developing a portfolio of next-generation cell therapies for cancer. It has a pipeline of therapies in clinical development for the treatment of hematological malignancies and solid tumors.

Tessa’s lead autologous therapy is in late-stage clinical development for treatment of lymphomas. It has shown strong clinical responses in patients with relapsed/refractory classical Hodgkin lymphoma, based on which it was granted the RMAT designation by the U.S. FDA and the PRIME designation by EMA.

Tessa is also developing a novel, differentiated, allogeneic “off-the shelf” cell therapy platform to create more efficacious, reliable, and scalable therapies capable of targeting a broad range of cancers. A therapy using this platform is being evaluated in an ongoing clinical trial in United States.

**Job Position**
(Senior) Scientist, Process Sciences

**Responsibilities**
- Be part of the Process development team, by setting up process parameters and development pipelines for various process
- Experimental design for optimization process parameters and process characterization
- Contribute to process validation/ characterization activities by performing supporting laboratory scale studies
- Work closely with Process experts, to carry out small-scale process development & optimization experiments
- Participate in Tech Transfer of process to manufacturing if needed
- Support process related investigation via lab-based experiment
- Interpret analytical data provided by the analytical team to define subsequent steps
- Provide scientific guidance to the associate scientist and support in troubleshooting
- Adapt new methods to existing procedures and modify current experiments through scientific knowledge and intuition.
- Follow health and safety procedures and implement paperwork as required

**Requirements**:

- Degree in a relevant Science Field or Equivalent Engineering or Biotechnology or any related field
- At least 4-6 years of related experience in process development work
- Practical laboratory experience in cell culture
- Knowledge/ experience with cell therapies
- Experience in Flow cytometry and ELISA assays
- Familiarity with DoE methodologies
- Ability to communicate effectively
- Good problem solving, and teamworking skills
- Strong analytical skills including critically and objectively/ logical thinking
- Strong time-management and organization skills

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