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Senior Research Fellow, Therapeutic target discovery LKCMedicine

2 weeks ago


Singapore Nanyang Technological University Singapore Full time

Senior Research Fellow, Therapeutic target discovery (LKCMedicine)

Join to apply for the Senior Research Fellow, Therapeutic target discovery (LKCMedicine) role at Nanyang Technological University Singapore .

The Lee Kong Chian School of Medicine (LKCMedicine) trains doctors who put patients at the centre of their care. Established in 2010 by Nanyang Technological University in partnership with Imperial College London, LKCMedicine aims to be a model for innovative medical education and transformative research. The School's primary clinical partner is the National Healthcare Group.

We are seeking an experienced scientist to lead therapeutic target discovery efforts, focusing on in vivo functional genomics related to metabolic syndrome and liver disease, with responsibilities including target identification, validation, and IP generation.

Key Responsibilities

  • Collaborate with physicians, bioinformaticians, industry partners, and researchers
  • Conduct in vivo functional genetic screens using mouse models
  • Analyze data to identify potential therapeutic targets
  • Validate targets in vivo and in vitro
  • Determine mechanisms of therapeutic effects
  • Supervise students and interns
  • Prepare protocols, grants, and scientific publications

Requirements

  • PhD in relevant discipline
  • Minimum 10 years of relevant experience with hands-on skills in mouse handling and genetic screens
  • Knowledge of IACUC and safety regulations in Singapore
  • Excellent communication skills
  • Proficiency in mouse handling, stem cell culture, NGS and data analysis
  • Experience in grant writing and scientific publishing
  • Ability to work independently and collaboratively under tight deadlines
  • Leadership skills and international experience

Additional Details

  • Seniority level: Mid-Senior level
  • Employment type: Full-time
  • Job function: Research, Analysis, IT
  • Industry: Higher Education
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