Principal /Senior Scientist (Oncology Discovery), EDDC
1 week ago
Principal /Senior Scientist (Oncology Discovery), EDDC At EDDC, our goal is to discover and develop novel therapeutics by working collaboratively with public sector and industry partners. We are recruiting a highly motivated Principal / Senior Scientist in the Oncology Discovery team. The successful candidate will provide strategic and scientific leadership for interdisciplinary drug discovery oncology projects, from target exploration and validation to drug candidate selection. Principle Roles & Responsibilities Strategic Leadership : Provide visionary direction and lead a team of cross‑functional scientists to drive the discovery of novel biologics for solid tumors, setting research priorities, goals and objectives. Target Identification : Lead efforts and incorporate innovative approaches to identify and validate novel oncology targets, leveraging multi‑omics analysis of clinical patient datasets and preclinical models. Compound Development : Develop a holistic and robust screening workflow for evaluating preclinical efficacy and safety of biologics. Oversee the screening and characterization of biologics compounds, collaborating closely with the antibody technology group. Assay Development : Develop and drive the creation and supervision of cellular assays including flow cytometry, internalization, immune‑cell mediated cytotoxicity (ADCC, TDCC), T cell proliferation, cytokine analyses and reporter assays for target validation and functional characterization of biologics. Supervise molecular cloning, stable cell‑line generation, CRISPR/Cas9 genome editing, siRNA/shRNA knockdown and qPCR. Data Analysis : Implement state‑of‑the‑art data analysis packages and interpretation approaches to make informed decisions in therapeutic drug discovery for biologics. Regulatory Compliance : Ensure research activities adhere to applicable regulatory guidelines and standards, supervise laboratory housekeeping, safety checks, SOP writing and participate in regulatory submissions as required. Qualifications and Requirements Ph.D. in a relevant field (e.g., oncology/immuno‑oncology, immunology, pharmacology) with extensive experience in oncology‑focused drug discovery in biologics modalities. Minimum 8 years of working experience with proven leadership experience, including managing scientific teams in the biopharmaceutical or biotechnology industry. Strong knowledge of molecular and cellular oncology, genetics, cancer biology, with expertise and in‑depth understanding of drug discovery and development of biologics. Exceptional communication and collaboration skills, with the ability to work effectively in cross‑functional teams. Strategic thinker capable of making informed decisions based on data and research insights. Possess strong interpersonal skills and collaborative spirit. Seniority level: Associate Employment type: Full‑time Job function: Research, Analyst, and Information Technology Industry: Research Services #J-18808-Ljbffr
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Singapore A*STAR RESEARCH ENTITIES Full timeAt EDDC, our goal is to discover and develop novel therapeutics by working collaboratively with public sector and industry partners. EDDC now has an opening and is seeking to recruit a highly motivated Principal / Senior Scientist in the Oncology Discovery team. The successful candidate will provide strategic and scientific leadership for inter-disciplinary...
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Bioinformatics/Data Scientist
5 days ago
Singapore A*STAR Research Full timeBioinformatics/Data Scientist (Computational Biology, EDDC)Overview At EDDC, Singapore's national platform for drug discovery and development, we are committed to discovering and developing novel therapeutics by working collaboratively with both public sector and industry partners, translating innovations from bench to clinic. This includes tackling complex...
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Scientist I/Scientist II
5 days ago
Singapore A*STAR RESEARCH ENTITIES Full timeAbout EDDC EDDC is a national platform committed to developing innovative therapies that have the potential to transform patients\" lives. Our research and development efforts are focused on understanding the underlying mechanisms of disease and translating these insights into effective treatments. We collaborate with both public sector and industry partners...
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Scientist I/Scientist II
8 hours ago
Singapore A*STAR RESEARCH ENTITIES Full timeAbout EDDC EDDC is a national platform committed to developing innovative therapies that have the potential to transform patients" lives. Our research and development efforts are focused on understanding the underlying mechanisms of disease and translating these insights into effective treatments. We collaborate with both public sector and industry partners...
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Software Developer
5 days ago
Singapore A*STAR Research Full timeSoftware Developer (Automation and Integration), EDDC Posting Date : 30 Jul 2025 | Closing Date :30 Sep 2025Overview: EDDC is the national platform for drug discovery, committed to work with the Singapore ecosystem to translate scientific discoveries into life-changing therapeutics for patients. We leverage state-of-the-art computational and machine learning...
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Singapore A*STAR - Agency for Science, Technology and Research Full timePrincipal Scientist / Senior Principal Scientist – Program Lead for Accelerated Materials Innovation (IMRE) Join A*STAR – Agency for Science, Technology and Research as a leading visionary to drive high‑throughput, AI‑driven experimental platforms for accelerated materials innovation. IMRE is seeking a technical leader with a proven track record in...
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Senior Scientist: Drug Discovery
5 days ago
Singapore Adecco Personnel Pte Ltd. Full timeA leading research-driven organization in Singapore is seeking a Senior Scientist to advance mid-size molecule projects in drug discovery. The ideal candidate holds a Ph.D. in a relevant field and possesses expertise in organic chemistry, peptide/nucleic acid chemistry, or chemical biology. Responsibilities include driving peptide identification and...
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Singapore A*STAR - Agency for Science, Technology and Research Full timeOverview Scientist/Senior Scientist, Discovery Platform (SIFBI) at A*STAR - Agency for Science, Technology and Research. This role explores microbiology and bioconversion related to food ingredient fermentation, bioactivity characterization, and related research activities. Responsibilities Contribute to the planning and execution of food ingredient...
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Senior Principal Research Scientist
5 days ago
Singapore Nanyang Technological University Full timeSenior Principal Research Scientist (Quantum Sensing Technology) page is loaded## Senior Principal Research Scientist (Quantum Sensing Technology)locations: NTU Main Campus, Singaporetime type: Full timeposted on: Posted Todayjob requisition id: is seeking a Senior Principal Research Scientist to lead a to lead the Centre for Quantum Sensing Technology...
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Senior Scientist, Discovery Research
1 week ago
Singapore Paratus Sciences Full timeGet AI-powered advice on this job and more exclusive features. Direct message the job poster from Paratus Sciences Biotech Leader | VP, Discovery Research | Built R&D sites & teams in Pharma & Biotech | Translating cutting-edge science into drug discovery... Company Overview Paratus Sciences ( is a biotech startup dedicated to improving human health by...
