
Biotechnologist (Purification)
6 days ago
Chromatography & Purification Operations (Core Focus)
Process Documentation & Compliance
Operate purification systems such as AKTA, TFF units, and chromatography columns (affinity, ion exchange, SEC, HIC).
Role Summary
We are looking for a motivated Biotechnologist, you will execute routine and critical manufacturing operations within the Purification area, ensuring consistent production of clinical and/or commercial biologics. You will operate and maintain bioreactors and related equipment in compliance with GMP guidelines and SOPs, contributing to process reliability and product quality.
Key Responsibilities
Chromatography & Purification Operations (Core Focus)
Operate purification systems such as AKTA, TFF units, and chromatography columns (affinity, ion exchange, SEC, HIC).
Prepare and formulate buffers, execute chromatography steps, and conduct in-process sampling and analytics (e.g., pH, conductivity).
Carry out column packing/unpacking, membrane filtration (UF/DF), and cleaning-in-place (CIP) routines.
Record activities and process parameters in electronic batch records (EBRs) or paper-based documentation according to cGMP standards.
Assist in troubleshooting purification deviations and contribute to root cause analysis.
Process Documentation & Compliance
Follow detailed SOPs, Master Batch Records (MBRs), and work instructions to ensure accurate and compliant operations.
Participate in process improvements, documentation updates, and equipment validation support where necessary.
Maintain proper housekeeping, 5S standards, and cleanroom protocols in purification suites..
Must-Have Qualifications
Studied in Biotechnology, Biochemical Engineering, Microbiology, or related life-science field.
Minimally internship experience of hands-on experience in chromatography.
Familiarity with GMP, GCP, and GDP standards in a biologics manufacturing environment.
Strong aseptic technique and cleanroom behavior.
Candidates with hands-on exposure to AKTA systems, column chromatography, or membrane-based separation will be strongly preferred.
Proficient in documentation.
We regret to inform that only shortlisted candidates will be notified.
EA Registration No: R ,
LEE YAO HONG MALCOLM
Allegis Group Singapore Pte Ltd, Company Reg No. N, EA License No. 10C4544
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