Scientist / Senior Scientist (LEE lab), A*SRL
2 weeks ago
We are seeking a highly motivated and skilled Scientist or Senior Scientist to join our dynamic research team at A*STAR. The ideal candidate will have a strong background in mouse disease models, cell and molecular biology, developmental biology, physiology, or related disciplines, and will play a key role in a well‐funded translational research project aimed at developing a novel therapeutic asset, with the goal of achieving spinoff or licensing readiness within 1‐2 years. This role provides a unique opportunity to bridge basic science and therapeutic innovation in a collaborative, fast‐paced environment with strong institutional support for commercialization. Key Responsibilities Design and execute in vivo mouse experiments, including animal handling, compound administration (e.g., IP/IV/SC), and tissue harvesting. Isolate primary cells from mouse or human tissues, cell culture of primary or immortalised mammalian cells. Engineering of stable cell lines by designing, generating, and using lentivirus or other transgenesis systems. Perform comprehensive tissue and cell analyses using: Histological techniques (e.g., fixation, embedding, sectioning, histological staining, immunohistochemistry)Biochemical assays (e.g., Western blotting, ELISA, enzymatic assays, serum biochemistry)Molecular biology techniques, including DNA/RNA extraction, PCR, qPCR, molecular cloning, and gene expression analysis. Bulk and single cell RNA sequencing. Microscopy (e.g., fluorescence, confocal, and brightfield imaging). Design and validate loss‐of‐function strategies (e.g., RNAi, CRISPR‐Cas9) for gene perturbation in vitro and in vivo. Analyze and interpret data. Maintain thorough laboratory records that will withstand regulatory scrutiny. Prepare technical reports, presentations, and manuscripts that may eventually contribute to regulatory applications (e.g. IND) and peer‐reviewed publications. Collaborate across multidisciplinary teams, including scientific, translational, and commercialization partners. Job Requirement Ph.D. in Cell/Molecular Biology, Developmental Biology, Physiology, Genetics, or a related field. Demonstrated hands‐on experience with mouse models, including compound dosing and tissue dissection, is required. Proficiency in primary cell isolation and culture, including from mouse or human tissues. Strong technical skills in histology, biochemistry, and microscopy‐based tissue analysis. Solid foundation in molecular biology and genetics, including construct design, cloning, RNAi, and CRISPR. Familiarity with single‐cell transcriptomics or related high‐dimensional platforms is advantageous. Excellent verbal and written communication skills, including the ability to present scientific findings clearly and effectively. Proven ability to complete and communicate scientific projects, as evidenced by at least one peer‐reviewed co‐first authored publication. Highly organized, self‐motivated, and capable of working independently and in cross‐functional teams. Needs to be able to maintain detailed laboratory records to be used for potential regulatory filings. Comfortable working with tight timelines and on a milestone‐gated project. Biotech industry experience is a plus. The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified. #J-18808-Ljbffr
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Scientist (Lay Lab), A*SRL
2 weeks ago
Singapore A*STAR - Agency for Science, Technology and Research Full timeScientist (Lay Lab), A*SRL Join to apply for the Scientist (Lay Lab), A*SRL role at A*STAR - Agency for Science, Technology and Research The Laboratory of Skin Stem Cell Dynamics, headed by Dr. Kenneth Lay, investigates how stem cells of the skin govern tissue homeostasis and contribute to disease pathogenesis so as to reveal novel pharmacological...
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Scientist / Senior Scientist (LEE lab), A*SRL
2 weeks ago
Singapore A*STAR - Agency for Science, Technology and Research Full timeOverview We are seeking a highly motivated and skilled Scientist or Senior Scientist to join our dynamic research team at A*STAR. The ideal candidate will have a strong background in mouse disease models, cell and molecular biology, developmental biology, physiology, or related disciplines, and will contribute to a translational research project aimed at...
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Principal Scientist I
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Singapore A*STAR RESEARCH ENTITIES Full timeA*STAR Biomedical Research Council invites exceptional candidates to apply for a Principal Scientist role within A*STAR Skin Research Labs (A*SRL), to commence in January 2026. A*SRL aims to create a translation-focused, clinically oriented, technology-proving, interdisciplinary skin R&D environment that increases its capacity to interact with industry...
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Scientist (Lay Lab), a srl
1 week ago
Singapore A*STAR Agency for Science, Technology and Research Full timeWe are looking for a Postdoctoral Fellow to join our laboratory in A*STAR Skin Research Labs (SRL) and affiliated with Skin Research Institute of Singapore (SRIS), a tripartite partnership between A*STAR, Nanyang Technological University (NTU) and National Skin Centre (NSC) to improve skin health in Asia and globally. **Duties and responsibilities**: Lead,...
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Scientist (Lay Lab), A*SRL
2 weeks ago
Singapore A*STAR RESEARCH ENTITIES Full timeRoles & Responsibilities The Laboratory of Skin Stem Cell Dynamics, headed by Dr. Kenneth Lay, investigates how stem cells of the skin govern tissue homeostasis and contribute to disease pathogenesis so as to reveal novel pharmacological intervention points. We focus on two stem cell populations that maintain distinct compartments of the skin throughout our...
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(Senior) Research Fellow/research Scientist
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Singapore A*STAR Agency for Science, Technology and Research Full timeThe A*STAR Skin Research Labs (A*SRL) Fellowship Programme aims to identify, mentor and nurture aspiring researchers in the field of skin research. The programme provides exceptionally talented and promising scientists, with a background in skin research or related areas, the opportunity to set up and independently run their own research projects. A*SRL...
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Scientist (Carlos Clavel lab), A*SRL
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Singapore A*STAR Research Full timeOverview A RSE2 Scientist position is available at the Hair & Pigmentation Development Laboratory within A*STAR Skin Research Labs, a partner in the Skin Research Institute of Singapore. This candidate will become part of our research group to elucidate mechanisms regulating hair morphogenesis, growth and regeneration. This project will take up 100% of...
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Central Lab Scientist
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Singapore Medpace Full timeJoin to apply for the Central Lab Scientist - Molecular role at Medpace Join to apply for the Central Lab Scientist - Molecular role at Medpace Our clinical laboratory activities are growing rapidly, and we are currently looking to add to our scientific team. The Scientist will act as a leader in the department and will participate in and direct research and...
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Scientist (Stefan Oehlers Lab), A*STAR IDL
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Singapore A*STAR - Agency for Science, Technology and Research Full timeJoin to apply for the Scientist (Stefan Oehlers Lab), A*STAR IDL role at A*STAR - Agency for Science, Technology and Research . 2 weeks ago Be among the first 25 applicants A*STAR Infectious Diseases Labs (A*STAR IDL) is seeking a Scientist to join us in our mission to be a leading centre of infectious diseases research. A*STAR IDL aims to develop a cohesive...
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Research Scientist
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Singapore A*STAR Research Full timeThe HY Lab is dedicated to advancing innovative cancer therapies, with a strong focus on translational research targeting cancer-specific mutations. Supported by major national and industry-aligned programs, our mission is to accelerate platform development and clinical translation. Our research spans antibody discovery and engineering, bispecific antibody...
