Molecular Biologist, Antimicrobial Resistance
3 days ago
Nanyang Technological University's Lee Kong Chian School of Medicine is seeking a highly experienced Research Fellow to join our team in the Respiratory and Infectious Diseases Programme. The successful candidate will work under the guidance of Professor Pablo Bifani, renowned expert in applied phage biology.
The primary focus of this role is to develop recombinant phages for treating multidrug-resistant organisms or recalcitrant bacterial infections. This research has the potential to revolutionize treatment options.
Main Responsibilities:- Perform standard microbiology techniques, including bacterial cultures and phage production, isolation, characterization, etc.
- Contribute to genetic manipulations/engineering of selected bacteriophages, such as knock-out, knock-in, mutagenesis, etc.
- Lead phage recombinant work in the lab
- Bacterial cultures
- Phage target deconvolution (understanding mechanisms of action and resistance of selected phages)
- Design and conduct experiments, including data collection and analysis
- Knowledge of bioinformatic tools would be beneficial
- Present data in lab meetings
- Develop new research techniques and approaches
- Manage grant and basic logistical requirements associated with the project
- Ensure safe technical practices and procedures
- PhD degree in Biomedical Sciences or related fields
- Background working with bacteria and strong foundation in molecular biology, including recombinant work, genomic, and transcriptomic research
- Expertise working with bacteriophages is an advantage
- Comfort working with various bacteria (drug-resistant K. pneumoniae, Acinetobacter, or Mycobacterium abscessus, others)
- Adaptability working with different organisms and techniques
- Collaborative spirit with internal and external collaborators
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