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Biochemistry Research Expert

1 week ago

Singapore NTU (Nanyang Technology University- Main Office-HR) Full time
Job Description

The School of Materials Science and Engineering (MSE) at Nanyang Technology University is seeking a talented Research Fellow to join our team. As a key member, you will play a crucial role in developing sensors and mitigants for bacterial contaminations in the cellular agriculture industry.

This exciting research project involves identifying potential target protein-protein interactions of bacteria, designing and synthesizing peptides derived from these PPI interfaces, evaluating their inhibitory activity and antimicrobial activity, and developing more advanced and active derivatives. You will work closely with our team to design, monitor, and perform experiments within the scope of the assigned research project.

Key Responsibilities:
  • Select the most important PPI for inhibition and design peptide inhibitors
  • Synthesize the designed peptides, purify and characterize them.
  • Express and purify the target bacterial proteins using recombinant systems.
  • Perform quantitative biochemical and biophysical studies of the protein-peptide interactions
  • Test the ability of the peptides to inhibit the target proteins and bacterial growth
  • Design improved more potent and stable peptides and test their activities as above
  • Use the best binding peptides for biosensor development
  • Conduct interpretation and application of experimental results
  • Gather information/ data and prepare documents for reporting/ papers and actively participate in all stages of writing these papers and reports
  • Assist in and deliver training and coaching new members with relevant laboratory/ technical skills