Structural Biologist

4 weeks ago

Singapore Nanyang Technological University Full time

Research Opportunity at the School of Biological Sciences

The School of Biological Sciences at Nanyang Technological University is a leading institution in the field of biological and biomedical sciences. Our research spans various areas, including infectious diseases, immunology, and genome function.

Join the laboratory of Xiao Tianshu at the School of Biological Sciences. We are seeking a Research Fellow to contribute to a project focused on structure- and function-based therapeutic development against infectious diseases, including flavivirus and coronavirus. The research fellow will be involved in experiments that will pinpoint novel antiviral inhibitors, structural characterization on the inhibitor/target interaction, and other mechanistic studies using biophysical and biochemical approaches.

Key Responsibilities

  • Protein production and sample preparation for cryo-EM
  • Data processing and analysis of cryo-EM using cryoSPARC, EMAN2, etc.
  • Functional studies to detect protein-inhibitor interaction and inhibitory activity
  • Data presentation

Job Requirements

  • PhD degree in structural biology, with focus on cryo-EM single particle analysis
  • Strong research experience and track record in protein structural study using Cryo-EM
  • Experience with molecular cloning, protein expression in mammalian cell/insect cell, and protein purification using affinity chromatography and FPLC system
  • Strong written and verbal communication skills in English
  • Excellent team player

The College of Science seeks a diverse and inclusive workforce and is committed to equality of opportunity. We welcome applications from all and recruit on the basis of merit, regardless of age, race, gender, religion, marital status, and family responsibilities, or disability.

We regret that only shortlisted candidates will be notified.

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