Principal scientist

2 weeks ago

Singapore Agency For Science, Technology And Research Full time

About EDDC: EDDC is a National platform dedicated to developing innovative therapies that transform patients' lives. Our research and development efforts are focused on uncovering the underlying mechanisms of disease and translating this knowledge into impactful treatments. We work collaboratively with public sector and industry partners to translate scientific discoveries arising from Singapore's biomedical and clinical sciences R&D into innovative healthcare solutions, with a focus on Asian-prevalent diseases. Position Summary: We are seeking a highly experienced subject matter expert in structural biology to lead and drive all aspects of protein science and related disciplines. The successful candidate will oversee protein science operations, including protein expression, purification, characterization (biophysical), and structural biology efforts, to support our drug discovery and development programs. This role demands a deep understanding of protein biochemistry and structural biology, and the ability to lead a multidisciplinary team of scientists. The successful candidate will collaborate closely with other departments, including Discovery Biology and Medicinal Chemistry, to drive scientific innovation and therapeutic advancements. Key Responsibilities: Leadership & Management: Lead, train and mentor a team of scientists in protein science, structural biology, and related disciplines. Develop and implement strategic goals for the Protein Science and Structural Biology Group to advance EDDC's portfolio and platforms. Manage resources and timelines to ensure the successful execution of projects. Protein Science & Structural Biology: Oversee all aspects of protein expression, purification, and characterization, ensuring high-quality and reproducible results. Drive structural biology activities, including X-ray crystallography, cryo-electron microscopy (cryo-EM), and NMR spectroscopy, to elucidate protein structures and support drug discovery. Establish workflows for biophysical techniques to analyze molecular interactions and study complex formation. Collaborate with biologists and medicinal chemists to integrate structural data into drug design and optimization. Stay current with advancements in protein science and structural biology technologies and apply them to enhance technical capabilities. Cross-Functional Collaboration & Continuous Improvement: Collaborate with other functional groups to ensure alignment of protein science efforts with broader drug discovery and development strategies. Assert cross functional influence by offering technical expertise during scientific discussions. Identify, evaluate and implement new technologies, methodologies, and approaches to improve the efficiency and impact of protein science and structural biology efforts. Partner with external academic and industry collaborators to advance research initiatives and bring in new technologies. Qualifications: Ph. D. in Biochemistry, Structural Biology, Molecular Biology, or a related field. 10+ years of experience in protein science and structural biology, with a proven track record of leading successful research programs. Strong expertise in protein expression, purification, and structural biology techniques such as X-ray crystallography, cryo-EM, and NMR. Experience in leading and managing a multidisciplinary team of scientists. Excellent communication and interpersonal skills, with the ability to collaborate effectively across departments. Proven track record of contributing to drug discovery and development projects. Experience with automation and high-throughput protein production is a plus. The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified. #J-18808-Ljbffr

  • Principal AI Scientist

    4 weeks ago

    Singapore Aon Hewitt Full time

    Principal AI Scientist Aon is in the business of better decisions At Aon, we shape decisions for the better to protect and enrich the lives of people around the world. As an organization, we are united through trust as one inclusive, diverse team, and we are passionate about helping our colleagues and clients succeed. About ACIA Aon’s Centers for...

  • Principal ai scientist

    2 weeks ago

    Singapore Aon Hewitt Full time

    Principal AI Scientist Aon is in the business of better decisions At Aon, we shape decisions for the better to protect and enrich the lives of people around the world. As an organization, we are united through trust as one inclusive, diverse team, and we are passionate about helping our colleagues and clients succeed. About ACIA Aon’s Centers for...

  • Principal ai scientist

    2 weeks ago

    Singapore Aon Hewitt Full time

    Principal AI Scientist Aon is in the business of better decisions At Aon, we shape decisions for the better to protect and enrich the lives of people around the world. As an organization, we are united through trust as one inclusive, diverse team, and we are passionate about helping our colleagues and clients succeed. About ACIA Aon’s Centers for...

  • Principal AI Scientist

    4 weeks ago

    Singapore Aon Hewitt Full time

    Principal AI Scientist Aon is in the business of better decisions At Aon, we shape decisions for the better to protect and enrich the lives of people around the world. As an organization, we are united through trust as one inclusive, diverse team, and we are passionate about helping our colleagues and clients succeed. About ACIA Aon’s Centers...

  • Principal AI Scientist

    4 weeks ago

    Singapore Aon Hewitt Full time

    Principal AI Scientist Aon is in the business of better decisions At Aon, we shape decisions for the better to protect and enrich the lives of people around the world. As an organization, we are united through trust as one inclusive, diverse team, and we are passionate about helping our colleagues and clients succeed. About ACIA Aon’s Centers...

  • Principal Research Scientist

    3 weeks ago

    Singapore Careers@Gov Full time

    Clean Energy Research CentreWe are seeking a highly experienced Principal Research Scientist to lead our research team in the field of sustainable energy. As a key member of our centre, you will be responsible for developing research ideas and proposals, securing funding, and leading research initiatives in areas such as PEM fuel cells, electrolyzers, and...

  • Sr. Scientist, Principal Scientist, Sr. Principal Scientist, Advisor, Sr. Advisor

    4 weeks ago

    Singapore Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Principal Scientist, R&D Skin Health

    4 weeks ago

    Singapore Kenvue Full time

    Come work at the forefront of science - and help the brands you grew up with grow and evolve into the next generation. Job Description - Principal Scientist, R&D Skin Health (2407024838W) Principal Scientist, R&D Skin Health Description Kenvue is currently recruiting for: Principal Scientist, R&D Skin Health This position reports into R&D Senior Manager...

  • Senior principal scientist, srtt q.inc

    2 weeks ago

    Singapore Agency For Science, Technology And Research Full time

    Job Overview: The Institute of Materials Research and Engineering (IMRE) is a research institute of the Agency for Science, Technology, and Research (A*STAR). Quantum Innovation Centre (Q. In C) is an A*STAR-level entity hosted within IMRE. Q. In C and IMRE are looking for a senior principal quantum scientist who has sufficient experience and proven track...

  • Sr. scientist, principal scientist, sr. principal scientist, advisor, sr. advisor

    2 weeks ago

    Singapore Eli Lilly And Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Sr. scientist, principal scientist, sr. principal scientist, advisor, sr. advisor

    4 days ago

    Singapore This Is An IT Support Group Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Principal scientist

    1 week ago

    Singapore Agency For Science, Technology And Research Full time

    Principal Scientist for Advanced Photonics and Flat Optics Process Integration The candidate will take the lead for the development of advanced photonics and flat optics integration. This could include but not limited as photonic integration, photonic heterogeneous integration, multi-layered flat optics integration, electro-photonics integration, etc.,...

  • Principal scientist, a*star id labs

    2 weeks ago

    Singapore Agency For Science, Technology And Research Full time

    A*STAR Infectious Diseases Labs (A*STAR ID Labs) is seeking for a Principal Scientist to join us in our mission to be a leading centre of infectious diseases research. A*STAR ID Labs aims to develop a cohesive A*STAR response to drive and deliver translational infectious diseases research to better health and economic outcomes. Job Description Leads...

  • Principal investigator/ scientist in food oral processing, sensory science

    2 weeks ago

    Singapore Agency For Science, Technology And Research Full time

    Principal Investigator/ Scientist in Food Oral Processing, Sensory Science and Oral Processing (SIFBI) SIFBI seeks to appoint a Principal Investigator in the area of food oral processing. Special interests will be on food oral manipulation, food oral rheology, oral tribology, oral physiology, bolus formation and swallowing, food-saliva interactions, and...

  • Principal Research Scientist

    2 months ago

    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    ANGEL invites applications for the position of Principal Research Scientist.Key Responsibilities: Support the Director in providing strategic direction and leadership to guide the center of excellence in achieving its vision and mission.Assist the Director in offering scientific insights and strategic direction for research collaborations with industry...

  • Principal Research and Development Scientist

    1 day ago

    Singapore Tate & Lyle Full time

    About This RoleWe're looking for a highly skilled Research Scientist/Senior Research Scientist to join our team at Tate & Lyle. As a key member of our R&D and Solutions Innovation group, you will play a crucial role in leading technical projects and developing innovative solutions for the food industry.

  • Principal Scientist

    3 weeks ago

    Singapore A*STAR RESEARCH ENTITIES Full time

    Roles & ResponsibilitiesPrincipal Scientist for Advanced Photonics and Flat Optics Process IntegrationThe candidate will take the lead for the development of advanced photonics and flat optics integration. This could include but not limited as photonic integration, photonic heterogeneous integration, multi-layered flat optics integration,...

  • Senior/principal scientist in human nutrition, sifbi .

    2 weeks ago

    Singapore MDIS Pte Ltd Full time

    A*STAR is seeking to appoint aSenior/Principal Scientist for the Clinical Nutrition Research Centre (CNRC). The CNRC, ajoint venture with National University of Singapore (NUS), is an integral part of Singapore Institute for Food and Biotechnology Innovation (SIFBI)'s nutrition capability. The CNRC is the most comprehensively equipped nutrition research...

  • Principal Research Scientist

    6 months ago

    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    The Air Traffic Management Research Institute (ATMRI), established in 2013 through a strategic partnership between NTU and the Civil Aviation Authority of Singapore (CAAS), is a premier institution dedicated to advancing the science and technology of air traffic management. ATMRI aims to enhance the efficiency, safety, and sustainability of the worldwide air...

  • Principal Scientist, HI, IME

    2 months ago

    Singapore A*STAR RESEARCH ENTITIES Full time

    Roles & ResponsibilitiesScientist/Senior scientist will be part of heterogeneous integration group focused on development of the quantum packaging technology platforms to integrate qubit and control chip on superconductivity interposer.He/she will work with cross functional team to: Design and simulation of superconducting circuits for salable quantum...