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Manufacturing Engineer

1 month ago

Singapur, Singapore 825 Glaxo Wellcome Manufacturing Pte Ltd Full time

To supervise, execute and monitor the activities within the value stream to ensure reliable and optimal operation of processes, equipment, utility and facility so as to achieve target production levels within the framework of current Good Manufacturing Practice (cGMP), quality, safety, occupational hygiene and environment protection.

Co-ordinate with the relevant parties and contribute to the development of the monthly production schedule to enable timely material support to production, and to optimize the production of bulk drug substances so as to minimize holding costs of intermediate goods.

Assess situation, plan and implement all process campaign turnaround activities, as well as co-ordinate and track progress of shift teams to ensure production plan adherence.

Identify and implement improvement to plant facilities, processes, methods of operations and turnaround, troubleshoot for process and equipment problems to minimize safety and quality risk as well as to ensure greater operational efficiency.

Lead or support quality or safety related investigation using appropriate problem solving tool to determine the root causes and implement CAPA to prevent recurrence.

Initiate, coordinate, plan and participate in plant modification activities, in the implementation of capital projects, project commissioning and tie-in.

Conducts audits and investigations, participate in audit preparation and complete identified actions in the assigned work area(s), in order to ensure compliance with GMP and safety requirements.

Prepare documents relating to manufacturing, plant turnaround, Work Instructions (WI), Local Standard Operating Procedures (SOP) and training manual to ensure that updated documents exist to support the activities of the operations department, schedule plan orders, and materials assignment. Documentation should comply to Data Integrity requirements and adherence to ALCOA principles.

Provide inputs to Periodic Product Review, Computer System Review and Cleaning Validation Review, Engineering Technical Review.

Support the Manufacturing Manager in new product introduction or plant trials and prepare and complete all necessary documents related to plant trial within the stipulated timeline.

Participate in the qualification works at OQ and PQ phases.

Provide M-ERP Support as BPE if assigned.

Raise and coordinate change control implementation and follow up on closure of change control.

Ensure availability of equipment, tools, production consumables, transfer of input materials as part of campaign preparation and follow up on ensuring housekeeping of above upon campaign ending.

Good honours degree in Chemical Engineering, no experience required

Up to 3 years of relevant experience in pharmaceutical, chemical or petrol-chemical industry.

Knowledge of product, production processes and the plant

Basic engineering knowledge

Basic statistical knowledge

Good troubleshooting skills

Knowledge of GMP, safety, hygiene and environment regulations

Basic project management skills

Effective communication skills

Auditing skills

To learn more about Singapore GSK and our people, please click on this link:

#Li-GSK 

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK.

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