Senior Research Associate, Antibody Production
1 week ago
**Senior Research Associate, Antibody Production Upstream**
Cell Line Development & Process Development - Singapore
**Senior Research Associate, Antibody Production Upstream**:
- Hummingbird Bioscience**
(Full-time position - Singapore based location)
**ABOUT HUMMINGBIRD BIOSCIENCE**
Hummingbird Bioscience is a data-driven precision biotherapeutics team discovering and developing transformative biologic medicines for hard-to-treat diseases. The Hummingbird Bioscience model combines computational and systems biology, wet lab drug discovery in a multi-disciplinary, collaborative environment spanning initial discovery through clinical development. We harness this integrated approach across target identification and patient selection, enabling our team to increase the efficiency of translating novel scientific insights while reducing the inherent risk in drug discovery and development. At Hummingbird Bioscience, our commitment to rigorous science, teamwork, and intellectual integrity underpins our passion to accelerate the journey of new drugs from concept to clinic.
**ABOUT THE ROLE**
**KEY RESPONSIBILITIES**
- Perform upstream process development/optimisation experiments through Design of Experiment
- Execute routine cell culture handlings for various CHO cell types and maintaining upstream analytical instruments such as NOVA Flex, Cedex Bio Analyzer, BGA, Octet or VCD/Viability Analyzer
- Conduct data analysis, interpret data and accurately document and communicate results
- Operate 50 L to 250 L CHO upstream Fed-Batch processes in single-use bioreactors (Thermo Fisher Hyclones)
- Conduct filter sizing study and operate depth filtration at 50 L - 250 L scale with Millistak pod system
- Support platform development including effective clone selection, high-throughput/time efficient process development from 5 L to 50 L, cutting-edge cell cultivation processes
- Identify issues, detect route to resolutions, for a study
- Organize internal data archiving, inventory keeping
- Author protocol, study reports and documents for technical transfer and regulatory filings
- Liaise with external and internal stakeholders as necessary to execute projects
- Able to adapt to a fast-paced work environment and perform under pressure
- Essential training will be provided
**ESSENTIAL QUALIFICATIONS**
- Bachelor of Science with 3-year relevant experience
- Master of Science with 1-year relevant experience
- Experienced with various CHO expression system, small to pilot scale bioreactor operations, fed-batch and perfusions
- Strong understanding in differences between RnD and manufacturing
- Basic understanding of biologics manufacturing, process development, scale-up, depth filtrations and single-use technologies
- Process validation experience is preferred
**OUR MISSION & VALUES**
Our fast-growing biotechnology company is committed to discovering and developing important new drugs for cancer and autoimmune diseases, and live by our values: Excellence, Determination, Teamwork, Intellectual Integrity and Audacity.
**JOIN US AT THE FRONTIER OF DRUG DISCOVERY AND DEVELOPMENT**
We are looking for passionate and motivated individuals committed to solving important, complex problems. We are committed to the personal and professional development of our team, with continually updated learning and development programs. Hummingbird Bioscience understands the need for flexibility for our team, offering a generous paid time off program with flexibility to support employees through different life stages. We invest in our team’s health by offering competitive health and wellbeing benefits including health and dental insurance, a comprehensive and holistic employee assistance program. We foster a more collaborative, productive, and sociable culture with on-site lunches and snacks. Finally, we believe in creating social impact beyond our business through corporate social responsibility initiatives.
- Hummingbird Bioscience is firmly committed to Equal Employment Opportunity (EEO) and to compliance with all Singapore and US federal, state and local laws and/or guidelines that prohibit employment discrimination on the basis of age, race, color, gender, sexual orientation, gender identity, ethnicity, national origin, citizenship, religion, genetic carrier status, disability, pregnancy, childbirth or related medical conditions, marital status, protected veteran status and other protected classifications._
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