Research Associate

2 weeks ago

Singapore Hummingbird Bioscience Pte. Ltd Full time

**Research Associate / Senior Research Associate, Antibody Production (Downstream)**

CLD & PD, Singapore

**Research Associate / Senior Research Associate, Antibody Production (Downstream)****:

- Hummingbird Bioscience**

(Full-time position - Singapore)

**ABOUT HUMMINGBIRD BIOSCIENCE**
- **Opportunity to work at the cutting edge of drug development**

Hummingbird Bioscience is an innovative clinical-stage biotech company focused on developing precision therapies against hard-to-drug targets to improve treatment outcomes. We harness the latest advances in systems biology and data science to better understand and solve the underlying causes of disease and guide development of our therapeutics.

Enabled by our proprietary Rational Antibody Discovery platform, we discover antibodies against optimal yet elusive epitopes on important targets that have not been successfully drugged, unlocking novel mechanisms of action. We are advancing a rich pipeline of first
- and best-in-class precision therapies in oncology and autoimmunity, in collaboration with global partners in academia and industry.

**ABOUT THE ROLE**

Join Hummingbird Bioscience on our journey as we transition from an early-stage drug discovery company, to a global leader in drug development. We are looking for an experienced Research Associate / Senior Research Associate, Antibody Production (Downstream)

**RESPONSIBILITIES (INCLUDING, BUT NOT LIMITED TO)**
- Execute routine purifications at various scales for standard IgG and IgG-like molecules, to reach targeted quality profile
- Conduct filter sizing studies at viral filtration and UFDF steps, conduct the scale-up operations at 50 L and 250 L scales
- Support and execute platform technology advancement, expanding research tools for tackle challenge molecules.
- Perform pilot scale processing using AKTA pilot, depth filtration using Millistak pod, viral filtration using Vpro Magnus device, ultrafiltration/diafiltration using AKTA Flux 6.
- Record data timely, accurately and legibly
- Support protein characterization studies using tools such as A280 protein concentration measurement, ELISA, silver stain, qPCR, protein kinetics study, LAL test and HPLC
- Author protocol, study reports and documents for technical transfer and regulatory filings
- Able to adapt to a fast-paced work environment and perform under pressure

**EXPERIENCE AND QUALIFICATIONS**
- Bachelor of Science with 3-year relevant experience
- Master of Science with 1-year relevant experience
- Strong understanding on monoclonal antibody and bispecific antibodies
- Strong understanding in differences between RnD and manufacturing
- Strong understanding of IgG therapeutic development from sequence to process development and biologics manufacturing process from vial thaw to drug product fill and finish
- Hummingbird Bioscience is firmly committed to Equal Employment Opportunity (EEO) and to compliance with all Singapore and US federal, state and local laws and/or guidelines that prohibit employment discrimination on the basis of age, race, color, gender, sexual orientation, gender identity, ethnicity, national origin, citizenship, religion, genetic carrier status, disability, pregnancy, childbirth or related medical conditions, marital status, protected veteran status and other protected classifications._

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