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Research Team Lead

3 weeks ago

Singapore MiRXES Pte Ltd. Full time

**Research Team Lead (Sequencing)**

MiRXES is a Singapore-headquartered molecular diagnostic company with R&D, manufacturing, and clinical lab operations in Singapore, USA, Japan, and China. We specialize in microRNA technologies and the development, manufacturing, and provision of diagnostic test kits and clinical services. Our mission is to enable early disease detection and provide insights for better patient care by harnessing the power of microRNA to augment traditional testing. Our vision is to be the world’s leading developer and provider of accurate, actionable, and affordable microRNA-powered diagnostic tests.

Job Location**: Helios**

**Job Summary**

MiRXES Lab is currently looking for an experienced team leader for our NGS team to work on our various research projects.

**Roles and Responsibilities**
- Personally perform and train junior team members on NGS workflows such as nucleic acid extraction, library preparation and sequencing.
- Perform literature search, design, plan, lead and/or conduct experiments for the optimization and validation for sequencing projects.
- Operationalize new protocols developed in-house, from commercial kits or from literature.
- Be cross-trained in other high-throughput workflows, e.g. miRNA RT-qPCR based profiling workflows as a secondary portfolio.
- Proactive and service-oriented data collection and organization for downstream data analysis, including coordination between teams for clarity on requirements and status of sequencing projects to aid decision making.
- Maintain an excellent record of experimental data and sample handling.
- Write and/or support preparation of technical reports, SOPs and documents.
- Validate procedures for instrument testing, quality control and generate final reports.
- Provide experimental and technical support to internal and external stakeholders whenever necessary.
- Inventory maintenance, forecasting and procurement of consumables and reagents.
- Provide support for compliance of health and safety policies.
- Any additional duties as assigned.

**Desired Skills and Competencies**
- Degree or post-graduate degree in a related Science/Engineering discipline. Extensive NGS experience with more than 2 years in a leadership position may be substitute this requirement.
- At least 4 years of molecular biology experience, with at least 2 years of experience in NGS and/or RT-qPCR. NGS experience which includes sample preparation to sequencer loading is preferred.
- Results oriented, with a high level of integrity, dependability, and project management skills.
- In-depth technical troubleshooting skills with regards to workflows of primary responsibility.
- Decision-making based on accurate and timely analyses, if necessary, with incomplete datasets.
- Ability to plan ahead and provide insights and alternatives for contingency.
- Excellent verbal communication, interpersonal and team skills.
- Demonstrate ability and confidence to work independently, within a team and across functional teams.
- Thrive in fast-paced environment pushing boundaries on known methods and protocols.