
Translational Insight Scientist
7 days ago
**Position: Translational Insight Scientist (Biomedical)**:
**Location**:Singapore
**Department**:Research & Development
**Reports To**:Senior Scientist / Bioengineering Lead
**Job Type**:Full-time
**Experience Level**:Mid-Level
**Position Overview**:
**Key Responsibilities**:
- Develop, maintain, and validate Organ-on-a-Chip (OoC) and organoid models to support drug testing, pharmacological studies, and response profiling.
- Perform functional and biochemical assays including TEER, ELISA, cytokine profiling, and viability/toxicity assessments to characterize model behavior.
- Handle human-derived primary and stem cell cultures, establish 3D microenvironments, and operate fluidic systems in chip and scaffold platforms.
- Optimize experimental protocols and troubleshoot biological and device performance across organoid and OoC systems.
- Interface with computational biology and AI teams by providing high-quality biological data and mechanistic context for in silico validation and inference.
- Interpret results within biological pathways involving barrier integrity, inflammatory responses, enzymatic activity, and cellular stress.Keep abreast of scientific developments in organoid biology, organ-on-chip, and translational microphysiological modeling.
**Minimum Qualifications**:
- Bachelor’s degree (B.Sc. or equivalent) in a relevant life sciences or bioengineering field
- Hands-on experience in cell culture, tissue engineering, or lab-on-a-chip systems.
- Familiarity with biological datasets (e.g., gene expression, imaging) and capacity to interpret them in collaboration with data specialists.
- Strong experimental and laboratory skills, with attention to reproducibility and detail.Effective communication skills and a collaborative approach to problem-solving.
**Preferred Qualifications**:
- Prior experience working with Organ-on-a-Chip, microfluidic platforms, or advanced in vitro models preferred.
- Conceptual understanding of bioinformatics tools (e.g., omics data, pathway mapping) from a biological user perspective.Experience in cross-functional teams involving data science, pharmacology, or systems biology.
**What We Offer**:
- A forward-thinking biotech environment addressing unmet needs in drug development and toxicology.
- Opportunities to collaborate with global experts in bioengineering, computational biology, and pharmacology.
- Competitive compensation and benefits package.Career development opportunities within the growing field of translational human-relevant research.
**How to Apply**:
Please submit your resume and a brief cover letter (including salary expectations) to:
Make sure to highlight your biotech experience and interest in microphysiological systems.
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