Scientist (Process Development)

**The Opportunity**

Esco Lifesciences Group provides enabling technologies, products and services to the life sciences and healthcare industries, supporting academic research and scientific discoveries, clinical practice, as well as biopharmaceutical R&D and manufacturing. Headquartered in Singapore, Esco has an extensive sales network in over 100 countries, direct sales and service offices in 24 countries, 8 manufacturing and R&D hubs in the US, Europe, the UK, China, Singapore, Indonesia, and over 1500 employees worldwide.

Esco is poised to benefit from the sustained growth of the healthcare and biopharma industries in Asia and globally. Esco has achieved market leadership in China, and globally, in multiple categories within some of the fastest growing segments — with China being its largest and fastest growing market. As a Singapore-headquartered company, Esco is a nexus of East and West, bridging technologies, products and talent across the world, with global operations spanning the US, Europe and Asia.

**Who we’re looking for**

**Physical/Mental Requirements/Work Environment**
- Ability to read, analyze and interpret scientific data and publications
- Ability to author or review protocols, technical reports and technology transfer documents.
- Ability to author or review standard operating procedures and other related documents.
- Ability to define problems, collect data, establish facts, and draw conclusions.
- Ability to focus
- Repetitive motions due to certain laboratory techniques

**Report To**:
Esco Aster.

One World Biosolutions for One Health.

**The Scope**

You will be part of Esco Aster’s scientific division and contribute to the company’s CDMO mission and objectives. You will perform research and process development activities, mainly in support of mammalian cells production, in collaboration with internal and external stakeholders, clients and partners.

Primary Work Location: Ayer Rajah Crescent, Singapore

**Responsibilities**:
**Design and Independently Execute Experiments**:

- Design and laboratory-scale experiments to support client upstream processes and requests.
- Perform assay development and data analysis.

**Upstream Process Evaluation and Optimization**:

- Evaluate and optimize existing client processes in preparation for scale-up.
- Propose improvements and modifications to enhance process efficiency.

**Scale-up and Technology Transfer**:

- Conduct scale-up experiments in larger bioreactors.
- Adapt processes to align with available on-site equipment.
- Facilitate technology transfer from clients, aiming at scaling up processes or implementing new technologies (e.g., perfusion, serum replacements).

**Continuous Process Improvement**:

- Proactively identify opportunities for process improvements.
- Initiate and drive enhancements to streamline processes.

**Project Management and Documentation**:

- Write client proposals, outlining milestones, timelines, and budgets for scale-up projects.
- Take ownership and accountability for all deliverables and milestones in assigned projects.
- Summarize project work in a formal report and communicate effectively to stakeholders.

**Cross-Functional Collaboration**:

- Collaborate across different teams to troubleshoot, test, and optimize various issues.
- Work seamlessly in a cross-functional environment.

**Subject Matter Expert Support**:
**Ad Hoc Tasks**:

- Undertake other tasks as assigned based on project needs.

**Flexible Work Schedules**:
Adapt work schedules as needed to accommodate cell culture schedules.

**Requirements**:

- Bachelor’s degree in Biology or related science.
- At least 4-5 years related laboratory experience including mammalian cell culture and stem cells.
- Experience with Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP) will be an advantage.
- Proficient in MS Office Suite (Microsoft Word, PowerPoint, Excel).
- Experience in isolation of stem cells, tissue banking and generation of cell bank.
- Experience with cell assays such as FACS, ELISA, biological assays.
- Experience with bioreactor systems.
- General laboratory skills, good pipetting skills and experience with automation.
- Strong computer, scientific, and organizational skills.
- Excellent communication (oral and written) and attention to detail.
- Strong team player, develop positive relationship with a strong set of interpersonal skills.
- Ability to work independently and as part of a team, self-motivated, adaptable, and has a positive attitude.
- Ability to learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.
- Good presentation skills.
- A friendly and pleasant disposition.