Senior Principal Scientist

2 weeks ago


Singapore Lonza Full time

Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

Did you know that we are the 1st biologics contract manufacturer in Singapore? We offer you exposure to upcoming biotech and established pharmaceutical companies and to the manufacturing technology needed to produce mammalian treatments and cell therapies of tomorrow. Our global manufacturing network is recognized for its reliable, high-quality services, regulatory track record, global footprint, innovative technology platforms and extensive experience - we, in Singapore are proud to be part of this global network.

As a Senior Principal Scientist - Global Process Development you will be specializing in upstream or downstream science. Provides scientific and technical solutions to complex project challenges across the Lonza mammalian network. Collaborates with global teams and customers to drive innovation and process improvements. Passionate about science and knowledge sharing, with a broad expertise in bioprocess development.

**Key responsibilities**:

- Provide strong scientific support for the development and manufacturing of therapeutic proteins using mammalian cell culture, with expertise in upstream (USP) or downstream (DSP) activities.
- Support pre-clinical and clinical process development, process transfer into cGMP, and execution of manufacturing processes.
- Lead multi-disciplinary teams to resolve technical, scientific, and IP-related issues using structured, data-driven approaches (e.g., RCA, risk assessments, DoE, FMEA, multivariate analysis). Ensure timely and well-documented investigation reports.
- Mentor and develop scientists within the Process Development team to enhance technical and analytical capabilities.
- Collaborate with R&D and operations to integrate innovative approaches and emerging technologies that improve Lonza’s operational efficiency and effectiveness.
- Maintain high scientific and quality standards for both customer and in-house projects, supporting regulatory inspections and interactions as needed.
- Monitor emerging trends in science, technology, and intellectual property (IP) that may impact Lonza’s business strategy and competitive positioning.
- Act as a scientific ambassador for Lonza, presenting at conferences, engaging with customers, and promoting Lonza’s capabilities externally.
- Effectively communicate complex scientific concepts to customers, internal stakeholders, and peers through presentations, reports, and discussions.
- Perform other duties as assigned to support business objectives and team success.

**Key Requirements**:

- A relevant Science degree such as a Bachelor in Biological Sciences / Chemical Engineering / Molecular Biology etc
- Able to articulate well and communicate abstract concepts to non-technical stakeholders effectively.
- Hands on knowledge of operational activities across multiple technical functions
- Experience in leading, delivering, and tracking projects across different regions

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.



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