Scientist (HWP Lab), IMCB

22 hours ago

Singapore Agency for Science, Technology and Research (A*STAR) Full time

Description:
Multi-omic analysis of secreted factors from various datasets was carried out, including human, mouse, and primate plasma and metabolic tissues to identify novel primate-specific secreted factors critically involved in the regulation of physiology balance. Integrative data analysis and in silico rank scoring revealed a list of promising secreted factor candidates. We will be using model organisms (e.g., mice, zebrafish) to conduct phenotypic screens and prioritize candidates for detailed validation, characterization, mode-of-action studies, and therapeutic strategies.
Job Responsibilities:
Conduct
in vitro
wet lab experiments for identified candidates (e.g., cell culture, molecular biology and assays, protein chemistry, pharmacological efficacy, etc.)
Conduct
in vivo
screening experiments for prioritized candidates (e.g., in preclinical models of obesity)
Conduct end-point and mechanistic experiments (e.g., target tissue and blood collection, sample preparation, etc.)
Analyze collected data and maintain accurate monitoring and reporting of experimental set-up, results, and research findings
Interact and collaborate with and assist other researchers and collaborators on related projects
Communicate regularly with supervisor and join discussions with Principal Investigator and rest of the lab to discuss scientific progress and direction
Assist in the preparation of grant applications and grant process reports
Present findings both orally and in written form via presentations and publication in peer-reviewed journals
Assist in the preparation of figures and manuscripts on the research projects for publication in peer-reviewed journals
Contribute to other program-related projects and organizations and with the general scientific community across A*STAR
Note:
The above eligibility criteria are not exhaustive. A*STAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.
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