Research Fellow/Senior Research Fellow
2 days ago
We are seeking a highly motivated Research Fellow to join Prof Mary Chan-Park's team. Our lab has recently secured a prestigious grant for the design, synthesis and studies of improved RNA delivery vehicles.
Prof Mary Chan-Park is the Centre Director of the Centre for RNA Delivery Therapeutics and President Chair Professor of Chemistry, Chemical Engineering and Biotechnology. She also holds a joint appointment at the Lee Kong Chian School of Medicine and is the Director of the NTU Laboratory for RNA Delivery Therapeutics and the Centre for Antimicrobial Bioengineering. She is a Fellow of the American Institute of Medical and Biological Engineering.
The successful candidate will play a key role in designing and synthesizing novel stimuli-responsive lipids or polymers for RNA delivery formulations to achieve efficient transfection and endosomal escape. This is a critical step towards replacing current delivery vehicles with more effective ones that have fewer side effects.
Key Responsibilities:
- Design and synthesize new stimuli-responsive lipids or polymers for RNA delivery formulations.
- Develop cationic or ionizable lipids or polymers for RNA delivery applications.
- Collaborate with team members to formulate lipids/polymers with RNA for transfection experiments.
- Measure and evaluate transfection efficiency, endosomal escape efficiency, and other particle properties.
- PhD in Chemistry, Chemical Engineering, Materials Science or related field.
- At least 5 years of relevant experience in lipid/polymer synthesis and design for stimuli-responsive nanoparticle delivery, particularly RNA delivery formulations.
- Familiarity with advanced lipid/polymer design for RNA delivery and nanoparticle formulations.
- Strong written and oral communication skills.
- Proficiency in lipid/polymer synthesis is essential.
- Competence in technical communication and leadership, including supervising junior researchers.
- Strong interpersonal skills, with the ability to work independently, meet deadlines and manage time effectively.
- Entry-level PhD graduates are welcome to apply.
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