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3 days ago
Job Description:
The successful candidate will be responsible for leading the design, execution, and troubleshooting of experiments related to microbial short-chain fatty acids (SCFAs) and their role in mucosal healing in ulcerative colitis. This includes conducting advanced molecular biology, immunology, and microbiome analyses, such as metagenomics, metabolomics, and immunophenotyping of colonic tissues.
Additionally, the researcher will develop and optimize small animal models of colitis to investigate the mechanistic role of SCFA-producing microbes in mucosal repair. Data analysis using computational pipelines for microbiome and metabolite profiling is also a key responsibility, ensuring high scientific rigor and reproducibility.
The position requires excellent laboratory and safety management skills, including adherence to biosafety, IACUC, and ORMC regulations. The researcher will train junior members in proper laboratory safety and animal ethics compliance.
Qualifications and Skills:
- Strong background in molecular biology, immunology, and microbiome research
- Experience with experimental design, data analysis, and computational pipeline development
- Excellent communication and teamwork skills
- Ability to work independently and manage multiple projects simultaneously
Deliverables and Outcomes:
- Drive publications in top-tier peer-reviewed journals arising from the project
- Support the generation of preliminary data for follow-up grant applications
- Contribute to achieving the manpower development KPI by training at least two Master's and Honours students during the project period
Benefits:
The successful candidate will have the opportunity to work on cutting-edge research in a dynamic and collaborative environment. They will receive comprehensive training and support to develop their skills and expertise, and will be part of a team that values innovation, creativity, and excellence.
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