AI Scientist, Generative AI Models for the Creation of RNA-Based Vaccines
2 weeks ago
AI Scientist, Generative AI Models for the Creation of RNA-Based Vaccines (GIS)2 weeks ago. Be among the first 25 applicants Overview The Genome Institute of Singapore (GIS) is the national flagship for genomic sciences, driving cutting-edge research at the intersection of biology, engineering, and medicine. This position is offered in the Laboratory of AI in Genomics, led by Prof. Mile Sikic, which uses advanced bioinformatics and deep learning approaches to develop next-generation models for genomic data analysis. We are a group of computer scientists with a mission to improve healthcare using advanced deep learning models. Located in the heart of Singapore's biomedical hub, GIS offers a dynamic and collaborative environment, with close ties to world-class universities (NUS and NTU), pharmaceutical companies, and biotech start-ups. Joining our team means working on transformative projects with real-world impact, while benefiting from Singapore's vibrant research ecosystem and strong support for innovation. Project background Messenger RNA (mRNA)-based therapeutics, including vaccines, represent a transformative class of drugs for infectious diseases and cancer immunotherapy. Their programmable nature allows rapid adaptation to evolving pathogens and personalized medicine, but effective design of mRNA molecules remains a key bottleneck. This project aims to develop an agent-based generative AI system to design both linear and circular mRNA molecules. By unifying the design process into a data-driven, adaptive pipeline, the system will optimize vaccine stability, minimize unwanted immune responses, and accelerate early-stage research and development from months to hours. The outcome will be a robust, scalable platform for creating effective mRNA vaccines for infectious diseases, cancer, and beyond. Job description We are looking for a highly motivated postdoctoral researcher to: Develop generative AI models for mRNA optimization Develop foundation models for mRNA assessment Run large-scale pretraining on high-performance computing infrastructure Perform model finetuning and hyperparameter optimization Evaluate models on experimental data Profile We welcome applications from candidates with: A PhD in computer science, computational biology, applied mathematics, physics, or a related field Proven experience in deep learning research and development Publication record at top-tier AI conferences (e.g., NeurIPS, ICLR, ICML, CVPR, ICCV, ACL, etc)Strong experience in Python programming and solid software engineering skills Experience with biomolecules and/or high-performance computing is a plus Interest in biology, biomolecules, or genomics (prior expertise not required)A structured, independent, proactive and collaborative working style We offer A fully funded position with an internationally competitive salary Professional development opportunities, including support for grant applications and participation in conferences and workshops Access to state-of-the-art research infrastructure, including NSCC's high-performance computing clusters A dynamic, interdisciplinary, and collaborative research environment The position is initially offered for one year, with the possibility of renewal. How to apply We look forward to receiving your application with the following documents: Letter of Motivation CV Diplomas & Transcripts We accept applications submitted through our online application portal or via email directed to Prof. Sikic at #J-18808-Ljbffr
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Scientist, Laboratory of AI in Genomics
5 days ago
Singapore A*STAR - Agency for Science, Technology and Research Full timeScientist, Laboratory of AI in Genomics (GIS)Join us at A*STAR - Agency for Science, Technology and Research as a Scientist, Laboratory of AI in Genomics (GIS) . Job duties and responsibilities: We seek talented individuals in computer science to advance cancer genomics research, utilizing artificial intelligence or classical algorithms. Your role will...
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Singapore A*STAR - Agency for Science, Technology and Research Full timeOverview Join to apply for the Scientist, AI in Drug Discovery, Laboratory of AI in Genomics (GIS)role at A*STAR - Agency for Science, Technology and Research The Genome Institute of Singapore (GIS) is the national flagship for genomic sciences, driving cutting-edge research at the intersection of biology, engineering, and medicine. This position is offered...
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Singapore PENSEES PTE. LTD. Full timeThe AI Developer, AI Scientist / Senior AI Scientist will be involved in the research and development for various fundamental and cutting-edge machine learning (ML), deep learning (DL), computer vision/speech algorithms as well as AI technology deployment into various platforms including PC, Cloud, and embedded system. **Responsibilities**: As an **AI...
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Singapore Outlier AI Full time**_FOR Singaporean English WRITING EXPERTS ONLY_** **Are you interested in helping to train AI models to become better writers? **How it works**: - We have several open projects where we are looking for talented writers to help train generative artificial intelligence models to become better writers. - You can work on all of our projects remotely. Hours...
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Singapore A*STAR Research Full timeOverview Scientist/Senior Scientist, RNA Analytical Development Job Title: Scientist/Senior Scientist, RNA Analytical Development Organization: Platform Technology Job Type: Full Time About NATi: The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore's national platform dedicated to advancing RNA-based medicines and revolutionizing...
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Singapore A*STAR Research Full timeScientist/Senior Scientist, Computational Oligonucleotide Design Posting Date : 18 Aug 2025 | Closing Date :17 Oct 2025Job Title: Scientist/Senior Scientist, Computational Oligonucleotide Design Organization: Platform Technology Job Type: Full Time About NATi: The Nucleic Acid Therapeutics Initiative (NATi), hosted by A*STAR, is Singapore's national platform...
