Biochemist Metabolomics Expert

4 days ago

Singapore beBeeBIOCHEMIST Full time

Research Officer

We are seeking a highly motivated Research Officer to join our team in a dynamic research environment.

Key Responsibilities:

  • Prepare biological samples for GC-MS and LC-MS metabolomics.
  • Extract phytochemicals from plant sources.
  • Handle tissue, stool, and plasma samples.
  • Perform plant-based protein extraction and characterization using gel electrophoresis, western blot, and prep-HPLC.

Instrumentation/Lab operation:

  • Operate and maintain LC-MS, GC-MS, QTOF-MS, Orbitrap-MS systems.
  • Conduct data acquisition and interpretation.
  • Maintain lab safety and hygiene.
  • Establish and update SOPs.
  • Provide technical support and general housekeeping.

Assay Development:

  • Execute cellular, genetic, biochemical, and drug screening assays.
  • Validate targets in vitro and in vivo using natural plant compounds.

Grant & publication support:

  • Participating in scientific discussions.
  • Presentation of research outcomes.

Administrative Duties:

  • Assist in procurement of laboratory supplies, consumables, and equipment.
  • Liaise with vendors and internal teams to ensure timely delivery of goods and services.
  • Update and maintain procurement records systematically.
  • Track and file invoices, delivery notes (DNs), and related documents.
  • Prepare documents for internal checks and external audits.

Requirements:

  • Bachelor or Master Degree in Chemistry, Biology, Biochemistry and related fields.
  • Carry out biological sample preparation for MS-based metabolomics (GC and LC), including the extraction of phytochemicals from plant sources.
  • Handling biological samples (tissue, stool and plasma samples).
  • Hand on the plant-based protein extraction and protein characterization with gel electrophoresis, western blot and prep-HPLC.
  • Synergize and execute cellular, genetic, biochemical, and drug screening assays in natural plants for validation of targets in vitro and in vivo.
  • Hand on the LC/GC instrumentations.
  • Contribute to project management, presentations, manuscript preparation & submission for publications.
  • Assist with general laboratory housekeeping, providing technical support, and establishing SOPs to ongoing research projects and maintaining good safety hygiene.
  • Participate actively in scientific discussions, present research outcomes and organize outreach programs to the scientific community and public.
  • Working experience with HPLC, LC-MS, QTOF-MS, Orbitrap -MS, GC-MS instrumentations, data acquisition and interpretation.
  • Experiences with metabolomics and proteomic sample preparation and data acquisition.
  • Some knowledge in microbiology, microbiome, and molecular biology, including DNA/RNA extraction.
  • Being able to multi-task with multiple projects and keep pace in dynamic research environment.
  • Good interpersonal communication skills with written, oral communication and computer skills.

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