Senior Scientist
2 days ago
Chugai Pharmabody Research Pte. Ltd. ("CPR") was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Biopolis in Singapore, we are committed to improve global heath through cutting- edge science and a passion of excellence. We continuously aim to generate new antibody drugs based on Chugai's proprietary antibody engineering technologies, such as recycling antibody, sweeping antibody, bispecific antibody to address unmet medical needs and deliver innovative therapeutics to patients globally. Position – Senior Scientist in Pharmacology Unit As we continue to grow, CPR is seeking a skilled and motivated Pharmacologist to join our dynamic R&D team. The candidate is expected to be a Ph.D. Scientist with expertise in in vitro and in vivo pharmacology studies. The candidate will have a strong background of molecular biology and be responsible for disease target validation. The candidate will lead antibody screening for drug discovery projects. Depending on the experience and opportunity, the candidate will also lead antibody drug discovery projects and participate in strategic discussions to advance programs through pipeline. Key Responsibilities: Design and conduct pharmacological studies to evaluate efficacy and mechanism of action of novel therapies Analyze and interpret data from in vitro and in vivo studies Mentor junior researchers and research associates Propose new drug discovery projects Draft publication or patent application with the support of IP specialists Job Requirements The applicant should be highly skilled in some of the following areas: Experience with drug discovery research (not limiting to antibody drug discovery) would be highly advantageous. Proficient in cell culture techniques with experience handling various mammalian cell lines Expertise in molecular biology techniques (e.g. generation of stable cell lines with overexpression, knockdown, and knockout of a gene, PCR, qPCR, Western blotting, ELISA). Experience with flow cytometry and cell sorting is preferred. Hands‐on in vivo experience is preferred. Qualifications PhD in Pharmacology, Life Sciences, or a related field. Proven experience in a pharmaceutical or biomedical research environment with at least 1-3 years of relevant experience. Strong knowledge of drug development processes, pharmacokinetics and pharmacodynamics is preferred. Demonstrate expertise in molecular or cell biology as evidenced by projects, presentations, or peer-reviewed scientific publications. Hands‐on experience with laboratory techniques and data analysis software (e.g. Graphpad Prism and excel). Excellent communication, teamwork and problem solving skills. We are looking for a scientist with a strong passion for creating and delivering innovative medicines to patients suffering from unmet medical needs. Experience and knowledge in antibody drug discovery would be an advantage but is not required. Excellent English (spoken and written), excellent organizational and communication skills, a team player mindset, and the ability to multitask are also required. Interested applicants are invited to email their detailed resume, as well as their qualifications, availability, current and expected salary to: For more information regarding our Company, you may refer to our website at: We regret that only short-listed candidates will be notified #J-18808-Ljbffr
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