Research Scientist, Infectious Diseases
6 days ago
Nanyang Technological University's Lee Kong Chian School of Medicine is seeking a highly motivated Research Fellow to join our team in the Respiratory and Infectious Diseases Programme. The successful candidate will work under the guidance of Professor Pablo Bifani, leading expert in applied phage biology.
The main focus of this role is to contribute to the development of recombinant phages for treating multidrug-resistant organisms or recalcitrant bacterial infections. The potential impact of this research could be life-changing.
Main Responsibilities:- Perform standard microbiology techniques, including bacterial cultures and phage production, isolation, characterization, etc.
- Focus on genetic manipulations/engineering of selected bacteriophages, such as knock-out, knock-in, mutagenesis, etc.
- Responsible for phage recombinant work in the lab
- Bacterial cultures
- Phage target deconvolution (understanding mechanisms of action and resistance of selected phages)
- Design and conduct experiments, including data collection and analysis
- Knowledge of bioinformatic tools would be beneficial
- Summarize and present data in lab meetings
- Develop new research techniques and approaches
- Perform maintenance of inventory and procurement of laboratory consumables
- Manage grant and basic logistical requirements associated with the project
- Ensure safe technical practices and procedures
- PhD degree in Biomedical Sciences or related fields
- Expected to have a background working with bacteria and a strong foundation in molecular biology, including recombinant work, genomic, and transcriptomic research
- Knowledge or expertise working with bacteriophages is an advantage
- Willngness to learn and comfort working with various bacteria (drug-resistant K. pneumoniae, Acinetobacter, or Mycobacterium abscessus, others)
- High adaptability in working with different organisms and techniques
- Collaborative spirit with internal and external collaborators
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Research Scientist
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