Structural Biology Expert

7 days ago


Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

About NTU Institute of Structure Biology (NISB)

NISB provides a complete pipeline for Structural Biology to accelerate discovery in basic and applied Bioscience. Our aim is to integrate a comprehensive set of Structural Biology tools to address fundamental questions in biology, to understand human diseases and to accelerate structure-based drug discovery.

We have the expertise and equipment to bring your gene of interest from plasmid to atomic level structure using a series of state-of-the-art platforms for Protein expression, biophysical characterization and imaging using cryo-EM, tomography or X-ray crystallography.

This role offers a unique opportunity to drive impactful research while fostering collaboration and innovation in a dynamic scientific environment. The job scope includes:

  • Main Responsibilities:
  • Collaborate with various academic and industry users of NISB facilities to define their needs and to help design and perform the experiments together with the core NISB team;
  • Lead the NISB core team to ensure timely delivery of quality samples and deliverables (overexpressed protein, structure with proper protocol and documentation;
  • Work with the core team to maintain accurate and comprehensive reporting and documentation for tasks commissioned by academic and industry users;
  • Support NISB Director in advocating for NISB's activities and technological platforms to enhance visibility and engagement with stakeholders;
  • Contribute to in-house research and platform technological development : the successful candidate can pursue independent research in structural biology or biotechnology aligned with the institute's interest in protein structure and engineering.

Key Requirements:

  • A PhD degree in Molecular Biology, Biochemistry, Structural Biology, Biotechnology or related field
  • At least 2 years of relevant experiences in similar role / technical hands-on experience in protein related work
  • Possesses international experience, acquired through postdoctoral experience documented by relevant publications
  • Good written and oral communication skills
  • Proficiency in handling software to collect and process Structural Biology data (XDS, CCP4, Phenix for X-ray crystallography and Cryosparc, Relion for Cryo-EM
  • Very good publication record in international peer reviewed journals in relevant fields
  • Strong ability to work independently, to develop solutions under strict timelines, meticulous and eye for details Excellent organizational and time management skills
  • Demonstrates strong collaboration skills by working effectively with diverse academic and industry stakeholders, as well as thriving in a fast-paced environment alongside the NISB core team


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