(Senior) Research Fellow, Department of Pathology

2 weeks ago

Singapore NATIONAL UNIVERSITY HOSPITAL (SINGAPORE) PTE LTD Full time
Job Description:

The Research Fellow will play a critical role at the intersection of clinical pathology and cutting-edge research, focusing on haematolymphoid malignancies. This unique position offers the opportunity to engage in advanced histological analysis of patient samples, manage and analyse complex tissue-based data, and contribute to innovative research projects. Successful candidate will have the chance to learn and apply the latest technologies in tissue-based research platforms, such as spatial transcriptomics, multiple immunofluorescence (MIF), and digital spatial technology (DSP). This role is ideal for individuals passionate about integrating clinical insights with research to drive forward our understanding of disease mechanisms and improve patient outcomes.

The Challenges

Responsibilities and Duties

You will be responsible for the following:

1. Histological Analysis:
  • Perform detailed histological examination of patient samples.
  • Identify and select samples that meet the inclusion criteria for various research projects in haematolymphoid malignancies.
  • Oversee the preparation of FFPE tissue for pathological tests including immunofluorescence and immunohistochemical staining for research purpose and construction of tissue microarrays.
  • Assist pathologists in the diagnosis and classification of haematolymphoid malignancies.

2. Data Management and Analysis:
  • Collaborate with bioinformaticians to analyse tissue-based research data, including multiple immunofluorescence (MIF), spatial transcriptomic profiling, digital spatial technology (DSP), bulk and single-cell RNA sequencing.
  • Manage and integrate clinical data with omics profiling data for comprehensive analysis.
  • Ensure the accuracy, integrity, and confidentiality of data.

3. Research Administration:
  • Participate in the design and execution of research studies involving patient tissue samples including obtaining the necessary approvals.

4. Supervision and Mentorship:
  • Assist PI to oversee interns, undergraduate and PhD students in the analysis of MIF, spatial transcriptomics, DSP, and RNA sequencing data.

Job Requirements:

Qualification :

• Medical Degree or Bachelor of Science and Bachelor of Medicine, with postgraduate training/certification in anatomic pathology

Experience :

• Extensive experience in histological analysis especially in haematolymphoid malignancies

• Excellent organizational, communication, and interpersonal skills.

• Ability to work independently and as part of a collaborative team.

Interested applicants are invited to email a detailed resume stating your current and expected salary to alliedhealth@nuhs.edu.sg

Please indicate in the subject title as: " Applying for position of "(Senior) Research Fellow, Department of Pathology"

We regret that only shortlisted candidates will be notified.

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