Senior Research Fellow

1 week ago

Singapore NANYANG TECHNOLOGICAL UNIVERSITY Full time
Roles & Responsibilities

The School of Chemistry, Chemical Engineering and Biotechnology (CCEB) invites applications for the position of Senior Research Fellow (Analytical Chemist, Oligo Synthesis and Analytics Development).

The key job purpose of the Analytical Chemist for oligonucleotide synthesis is the development and validation of analytic method development for oligonucleotide synthesis, and to support operations related to oligonucleotide synthesis, ensuring efficient and accurate production of high-quality oligonucleotides. This role involves working with a team of scientists, developing new and optimizing synthesis protocols in oligo modifications and conjugation, managing resources effectively, and fostering a culture of continuous improvement and innovation in oligonucleotide synthesis processes. This role aligns with the University's key research pillar of Future Health.

Key Responsibilities:

  • Development and validation of analytic method development for oligonucleotides
  • Establishment of analytic method workflow.

Job Requirements:

  • PhD in organic chemistry and relevant fields
  • Demonstrated track record in laboratory research, analytics process development esp in HPLC and LCMS

We regret that only shortlisted candidates will be notified.The School of Chemistry, Chemical Engineering and Biotechnology (CCEB) invites applications for the position of Senior Research Fellow (Laboratory Director). The key job purpose of the Senior Research Fellow (Laboratory Director) for oligonucleotide synthesis and GLP implementation is to oversee and manage all aspects of the laboratory operations related to oligonucleotide synthesis, ensuring the efficient and accurate production of high-quality oligonucleotides. Additionally, the Senior Research Fellow (Laboratory Director) is responsible for implementing and maintaining Good Laboratory Practices (GLP) standards within the laboratory to ensure compliance with regulatory requirements and to uphold the integrity of research data. This role involves leading a team of scientists, developing new and optimizing synthesis protocols in oligo modifications and conjugation, managing resources effectively, and fostering a culture of continuous improvement and innovation in oligonucleotide synthesis processes. This role aligns with the University's key research pillar of Future Health

Key Responsibilities:

  • Establishment of SOPs for oligo synthesis, purification and conjugation process
  • Analytical method development in accordance to international regulatory guidelines (ICH) for QC test method validation activities.
  • Overseeing GLP implementation (including the quality management system, documentation, SOPs and staff training), and will be responsible to sign off and ensure these GLP processes are followed
  • Innovate new synthesis steps in oligo modification and conjugation.
  • Completion of GLP-ready oligo synthesis integrated with conjugation capability and QMS development

Job Requirements:

  • PhD in organic chemistry and relevant fields with 4 years relevant experience
  • Demonstrated track record in cost effective synthesis of simple to complex organic molecules such as peptides, oligonucleotides (DNA, siRNA)
  • Demonstrated track record in capability building of oligosynthesis and purification

We regret that only shortlisted candidates will be notified.

Tell employers what skills you have

Cell
Teaching
Quality Management
Medicine
Chemistry
Purification
Biotechnology
Biology
Organic Chemistry
Characterization
Writing
Publications
Regulatory Requirements
Laboratory
Chemical Engineering
GLP

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