Scientist, Cell Bioassays

1 week ago

Singapore VECTURA FERTIN PHARMA LABORATORIES PTE. LTD. Full time
Roles & Responsibilities

Role Summary

Lead the organization's effort on test method development, validation, transfer and training with focus on cell-based and ligand binding assays using advanced system (i.e., Luminex, FACS, ELISA), clinical pathology using basic system (i.e., COBAS, STA, DXC, SYSMEX) and in-vitro cytotoxicity and genotoxocity assays to support the delivery of organization's study pipeline in the area of pre-clinical toxicology and pharmacology.

Provide technical leaderships to the analysts in Cell Bioassays department and support for day-to-day quality control operation.

As a technical subject matter expert, coordinate and liaise with cross-functional units and stakeholders (HODs, SDs, Sponsors, global counterparts) on the testing strategy and execution delivering to the study requirements.

Participate in evaluating and technical exchange with third party laboratory to ensure outsourced project meet technical and regulatory requirements.

Review and approve test results and assist on study planning for Cell Bioassays department in work flow optimization, resourcing, procurement etc. May be conducting routine test per project requirement and capacity constrain.

Responsibilities

· Act as a study director for the conduct of studies under Good Laboratory Practices (GLP). Ensure that all documents are prepared according to GLP standards and within the required timeframe. Supervise or perform the experimental phase of the study for both regulatory and exploratory studies. At the end of the study, ensure all documents are completed and participate in internal and external audits.

· Lead the organization's effort on test method development/optimization and validation focusing on cell-based and ligand binding assays (i.e. Luminex, FACS, ELISA) for the identification and quantitation of chemical constituents and metabolic biomarkers in complex matrices. Conduct in-vitro assays (AMES, MLA, WST8, NRU) for endpoint procedures using cell and bacterial cultures

· Provide technical leaderships to the analysts in Cell Bioassays department in the relevant technical domain; conduct training to the junior analysts and new hires; provide first-line technical support for daily smooth quality testing

· Coordinate outsourced bioassay activities at third party laboratory. Participate in evaluating and technical exchange with third party laboratory to ensure outsourced project meet technical and regulatory requirements

· Act as SME in the technical domain and be the point person to coordinate and liaise with cross-functional units and stakeholders (HODs, SDs, Sponsors and global counterparts) on the testing strategy and execution. Foster a culture of collaboration and enable frequent technical exchange across the network

· Review and approve test results and assist on study planning for Cell Bioassays department in work flow optimization, resourcing, procurement etc

· Conduct routine test per project requirement and capacity constrain, and assigned with operational tasks and improvement projects. The routine measurements includes performing cytotoxicity assays under the scope of ISO 17025

Requirement

· At least Bachelor Degree / M.Sc. in Chemistry, Life Sciences or related technical/scientific discipline is preferred

· Minimum 3 years relevant experience with technical and scientific knowledge with focus on bioassays method development, validation and laboratory operations, with a CRO, R&D unit within pharmaceutical or healthcare industries, or translational research organizations

· In-depth knowledge and preferably hands-on experience in workflows related to toxicology studies and life science research.

· Must possess experience in conducting studies under Good Laboratory Practices (GLP).

· Independent ability to develop, optimize, and validate assays such as Luminex, FACS, and ELISA-based methods in complex matrices.

· Understanding of regulatory guidelines such as FDA, ICH, OECD GLP, and TGs related to in vivo toxicology studies and method validation.

· Preferably hands-on experience with Clinical Pathology systems (COBAS, STA, SYSMEX, DXC, BIOANALYZER).

· Proficiency with ELN, SDMS, and LIMS in a regulated environment is a strong plus.

· Self-starter and highly motivated individual with excellent communication and influencing skills. Must be able to manage multiple diverse projects simultaneously.

· Good command of spoken and written English

· Proficient in MS word, Excel, Powerpoint.

Tell employers what skills you have

Influencing Skills
Translational Research
in Vivo
Cell
FDA
CRO
Biomarkers
ELISA
Chemistry
Pathology
LIMS
Resourcing
Pharmacology
Toxicology
Life Sciences
GLP

  • Bioassay Specialist

    4 weeks ago

    Singapore PRESTIGE BIOPHARMA LIMITED Full time

    Roles & ResponsibilitiesAbout the Job:We are seeking highly motivated and innovative Bioassay Research Specialists who are passionate about biologic drug development to join us in our fast-growing R&D Lab. The Research Specialist will work both independently and with Research Scientists to provide timely, high-quality support of multiple therapeutic...

  • Bioassay Specialist

    4 weeks ago

    Singapore PRESTIGE BIOPHARMA LIMITED Full time

    Roles & ResponsibilitiesAbout the Job:We are seeking highly motivated and innovative Bioassay Research Specialists who are passionate about biologic drug development to join us in our fast-growing R&D Lab. The Research Specialist will work both independently and with Research Scientists to provide timely, high-quality support of multiple therapeutic...

  • Junior QC Scientist

    4 weeks ago

    Singapore WUXI XDC SINGAPORE PRIVATE LIMITED Full time

    Roles & ResponsibilitiesJob Summary:The Junior QC Scientist is responsible for conducting a range of sampling, testing and operational quality control activities.Key Responsibilities:Conduct various analytical, bioassay and microbiological tests, including CE-SDS, cIEF, Karl Fischer titration, Total Organic Carbon (TOC) testing, UV-Vis...

  • Junior QC Scientist

    4 weeks ago

    Singapore WUXI XDC SINGAPORE PRIVATE LIMITED Full time

    Roles & ResponsibilitiesJob Summary:The Junior QC Scientist is responsible for conducting a range of sampling, testing and operational quality control activities.Key Responsibilities: Conduct various analytical, bioassay and microbiological tests, including CE-SDS, cIEF, Karl Fischer titration, Total Organic Carbon (TOC) testing, UV-Vis...

  • Materials Scientist Solid Oxide Fuel Cells

    5 days ago

    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    About Our TeamThe School of Mechanical and Aerospace Engineering (MAE) at Nanyang Technological University is a dynamic and multi-disciplinary international research community comprising world-class scientists and bright students. We pride ourselves in our excellent research capabilities in areas including advanced manufacturing, aerospace, biomedical,...

  • Cell Therapy Biotechnologist

    4 weeks ago

    Singapore ESCO ASTER PTE. LTD. Full time

    Roles & ResponsibilitiesThe OpportunityEsco Lifesciences Group is Singapore's most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in...

  • Senior Scientist

    1 week ago

    Singapore CHUGAI PHARMABODY RESEARCH PTE. LTD. Full time

    Roles & ResponsibilitiesChugai Pharmabody Research Pte. Ltd. ("CPR") was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd (Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Biopolis in Singapore, it aims to generate new antibody drugs based on Chugai's proprietary...

  • Scientist/Senior Scientist, EDDC

    4 weeks ago

    Singapore A*STAR RESEARCH ENTITIES Full time

    Roles & ResponsibilitiesAt EDDC, our goal is to discover and develop novel therapeutics by working collaboratively with the public sector and industry partners. EDDC now has an opening and is seeking to recruit a highly motivated Scientist/ Senior Scientist in the Oncology Discovery team. The successful candidate will participate and support...

  • Postdoctoral Research Fellow/Scientist

    4 weeks ago

    Singapore A*STAR RESEARCH ENTITIES Full time

    Roles & ResponsibilitiesResponsibilitiesThe lab of RNA in Disease and Translational Technologies at the Institute of Molecular and Cell Biology, A*STAR, Singapore is seeking to recruit a highly motivated Scientist or Senior Scientist to join a team developing a ribozyme-based RNA platform for potential translational and/or clinical applications.The ...

  • Mammalian Cell Culture Specialist

    7 days ago

    Singapore GenScript Full time

    About UsGenScript Biotech Corporation is a global leader in biotechnology, dedicated to making humans and nature healthier through innovation. Our business encompasses four major categories: Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.Job SummaryThis position involves working with...

  • MarCom Manager: APAC

    5 hours ago

    Singapore Cell Signaling Technology, Inc. Full time

    Who we are... Cell Signaling Technology (CST) is a different kind of life sciences company, one founded, owned, and run by active research scientists, with the highest standards of product and service quality, technological innovation, and scientific rigor for over 20 years. We consistently provide fellow scientists around the globe with best-in-class...

  • Research Scientist

    3 days ago

    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    The School of Mechanical & Aerospace Engineering (MAE) at Nanyang Technological University (NTU) is seeking a skilled Research Scientist to develop solid oxide fuel cells (SOFCs). This role offers a unique opportunity to work at the forefront of fuel cell research, focusing on the fabrication, synthesis, and characterization of materials for SOFCs.About the...

  • Cell Therapy Biotechnologist

    4 weeks ago

    Singapore ESCO ASTER PTE. LTD. Full time

    Roles & ResponsibilitiesThe OpportunityEsco Lifesciences Group is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 42 locations and 26 direct countries across North America, Europe, Asia, Oceania.Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first incorporated in...

  • Associate Scientist

    4 weeks ago

    Singapore RANDSTAD PTE. LIMITED Full time

    Roles & ResponsibilitiesAssociate Scientist – Viral Clearance12 month contractWork Your Magic with usReady to explore, break barriers, and discover more? We know you've got big plans – so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and...

  • Research Scientist

    3 days ago

    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    The Organelle Dynamics and Function Lab at NTU is seeking a highly motivated Research Scientist to join our team. As a key member of our research group, you will be responsible for conducting cutting-edge research using high-resolution light microscopy to study membrane, condensate, and organelle dynamics.You will investigate organelle dysfunction using iPSC...

  • Research Scientist

    1 week ago

    Singapore NEOCYTOGEN THERAPEUTICS PTE. LTD. Full time

    Roles & ResponsibilitiesNeocytogen Therapeutics, headquartered in Singapore, is a pioneering biotechnology company with scientific teams in Singapore and China. Our cutting-edge research harnesses the power of neoantigens to develop personalized treatments. We excel in advanced cell therapies, including allogeneic CAR-T and CAR-NK, designed to precisely...

  • Research Scientist Opportunity

    7 days ago

    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    We are seeking a highly skilled Research Scientist to join our team at Nanyang Technology University.Job DescriptionThe successful candidate will design and synthesize supramolecular systems for targeted drug delivery in cancer treatment.ResponsibilitiesDesign and synthesize supramolecular systems for targeted drug delivery in cancer treatment, including...

  • Research Scientist

    7 days ago

    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    Job DescriptionThe School of Chemistry, Chemical Engineering and Biotechnology at Nanyang Technology University is seeking a highly motivated Research Fellow to join the Nano-Bio Interface Lab.The lab focuses on elucidating the nanoscale regulation mechanism of how membrane geometry impacts cellular and biomolecular machineries in disease progression and...

  • scientist in in vivo pharmacology

    4 weeks ago

    Singapore OASIS BIO PTE. LTD. Full time

    Roles & ResponsibilitiesJob scope:1. Plan and/or execute experimental plans2. Troubleshoot technical problems3. Develop and optimize protocols4. Summarize and present literature and internal data in project meetings5. Other tasks assigned by supervisor.Requirement:Education level and requirements for hands-on experiences:Bachelor's degree with at least 2...

  • Research Scientist

    7 days ago

    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    The School of Chemistry, Chemical Engineering and Biotechnology at Nanyang Technological University invites applications for a research position in the Nano-Bio Interface Lab.Located in the School of Chemistry, Chemical Engineering and Biotechnology, the lab is led by Asst. Prof. ZHAO Wenting. The team is seeking a highly motivated individual to join their...