Process Development Scientist

2 weeks ago


Singapore GDMC PTE. LTD. Full time
"Any sufficiently advanced technology is indistinguishable from magic. -Arthur C. Clarke" _


At Genetic Design and Magic (GDMC), we aim to bring transformative genetic medicines to patients faster, improving their quality of life.

We achieve this by focusing on partnering and supporting early-stage companies and investigator with innovative therapeutic modalities such as gene therapy or mRNA drugs.

Leveraging on our expertise in process development and manufacturing, our partner companies can bring their ideas into the market as we work hand in hand with them through clinical trials.

We are growing quickly and looking for talented people who are looking out for challenging opportunities to bring transformative medicines and make an impact in people's lives.


As one of our Process Development Scientists (Downstream), you will be responsible for developing and executing downstream processes for products that we manufacture, building new processes, and closely collaborating with partner-clients / our in-house manufacturing team to optimise purification processes.

You will also be exposed to novel technologies in the biotherapeutic manufacturing pipeline. Join us in building a world-changing process development team housed in our state of the art multi-million biomanufacturing facility. If you'd like to play a part in bringing the next life-saving innovations to market, we want you

Responsibilities

  • Interact with the client partners on a daily or weekly basis to analyze their existing process for transferability and scalability.
  • Manage the internal process development technicians and interns in proper laboratory techniques and scientific experimental design as necessary.
  • Design and troubleshoot experiments for testing various unit operations in process development in accordance with clients need and company's overall strategic goals.
  • Develop and test novel purification strategies for Viral Vectors / mRNA / pDNA products.
  • Design and test process control strategies.

Requirements:

  • PhD in bioprocessing, pharmaceutical science, chemical engineering or equivalent for Lead role.
  • BSC/MSC+ a few years of lab experience (preferably working experience with AKTA) will be considered.
  • 15 years of work experience within bioprocessing, academic or commercial process development.
  • Demonstrable proficiency designing and troubleshooting downstream process experiments.
  • Demonstrated proficiency in a wide variety of analytical and DSP techniques (E.g., SEC, IEX).

Desired Qualifications

  • Familiarity with developing purification processes for viral vectors (AAV, Lentivirus, Retrovirus).
  • Experience in performing tech transfer processes.
  • Comprehensive understanding of cGMP requirements for biomanufacturing or pharmaceutical industries.
  • Familiarity in working with AAV specific purification resins (i.e., AAVX Affinity Resin).
  • Experience in encapsulation of mRNA in Lipid Nanoparticles or equivalent encapsulation methods.


  • Singapore ESCO ASTER PTE. LTD. Full time

    Roles & ResponsibilitiesThe OpportunityEsco Lifesciences Group, is Singapore’s most globalized life sciences company, with annual revenues close to SGD 200M and global operations in over 20 countries across North America, Europe and Asia.Esco Aster Pte Ltd is an affiliate of Esco Lifesciences Group and was first introduced in 2017.At Esco Aster Pte Ltd, we...


  • Singapore Recruit Express Pte Ltd Full time

    Process Scientist - Pharma MNC (12-Month Contract)Position: Process ScientistCompany: Pharma MNC Contract Duration: 12 MonthsLocation: TuasA leading global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines to improve health and well-being at every stage of life. Our commitment to research and development has...


  • Singapore Recruit Express Pte Ltd Full time

    Process Scientist - Pharma MNC (12-Month Contract)Position: Process ScientistCompany: Pharma MNC Contract Duration: 12 MonthsLocation: Tuas A leading global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines to improve health and well-being at every stage of life. Our commitment to research and development...


  • Singapore VALERE SG PTE. LTD. Full time

    Responsibilities Interact with the client partners on a daily or weekly basis to analyze their existing process for transferability and scalability. Manage the internal process development technicians and interns in proper laboratory techniques and scientific experimental design as necessary. Design and troubleshoot experiments for testing various unit...

  • Research Scientist

    1 month ago


    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    We invite suitable candidate to join a strong research team in Temasek Laboratories@NTU as a Research Scientist.Key Responsibilities:Conduct research in digital signal processing, in particular the detection and localization of active and passive targets via wireless RF signals in the harsh environmentConduct both theoretical development of methods and...

  • Research Scientist

    2 months ago


    Singapore NTU (Nanyang Technology University- Main Office-HR) Full time

    We invite suitable candidate to join a strong research team in Temasek Laboratories@NTU as a Research Scientist.Key Responsibilities:Conduct research in digital signal processing, in particular the detection and localization of active and passive targets via wireless RF signals in the harsh environmentConduct both theoretical development of methods and...

  • Development Scientist

    2 weeks ago


    Singapore Affinity Human Venture LLP Full time

    Product Development Scientist, Wet PetfoodLocation: SingaporeCompany: R&D CenterSingapore Type of contract: PermanentA fantastic job opportunity with a global FMCG company specialized in human and animal nutrition.Position Summary Provide product/process expertise and assistance within the Center and externally (e.g., with Marketing, Manufacturing,...


  • Singapore A*star Research Entities Full time

    The Advanced Remanufacturing and Technology Centre (ARTC) is a public-private partnership consortium of more than 80 industry members. Our core mission is to develop and deploy advanced manufacturing solutions and upskill the workforce to drive local industry competitiveness. Smart Virtual Systems (SVS) Group is seeking a highly motivated Scientist/ Senior...


  • Singapore Singtel Full time

    Associate Data Scientist - #catalystWSP:Date:06-Feb-2023Location: Singapore, SingaporeCompany:Singtel GroupWe are looking for an Associate Data Scientist within the Group Enterprise business of Singtel.Key Responsibilities: Develop models and perform statistical analysis to identify key insights in enterprise customer experience, pricing prediction or...


  • Singapore A*STAR RESEARCH ENTITIES Full time

    Roles & ResponsibilitiesThe Advanced Remanufacturing and Technology Centre (ARTC) is a public-private partnership consortium of more than 80 industry members. Our core mission is to develop and deploy advanced manufacturing solutions and upskill the workforce to drive local industry competitiveness. Smart Virtual Systems (SVS) Group is seeking a highly...


  • Singapore A*STAR RESEARCH ENTITIES Full time

    Roles & ResponsibilitiesThe Advanced Remanufacturing and Technology Centre (ARTC) is a public-private partnership consortium of more than 80 industry members. Our core mission is to develop and deploy advanced manufacturing solutions and upskill the workforce to drive local industry competitiveness. Smart Virtual Systems (SVS) Group is seeking a highly...


  • Singapore Affinity Human Venture LLP Full time

    Product and Process Development ManagerLocation: Singapore, TuasCategory: RESEARCH & DEVELOPMENTJob Purpose and ImpactThe Product and Process Development Manager will provide technical contributions to the development of ingredients and actively lead the day-to-day operating activities of the team within a specific department. In this role, you will provide...

  • AI Research Scientist

    2 weeks ago


    Singapore HyperGAI Full time

    We are looking for extraordinary research scientists in the Multimodal Generative AI field. As a research scientist, you discover new research problems, develop novel methods, train new models, design comprehensive experiments, and generally advance the state of the art in Generative AI. Research scientists have the opportunities of choosing their research...

  • Scientist (IMRE)

    3 weeks ago


    Singapore A*star Research Entities Full time

    Job Overview:The Institute of Materials Research and Engineering (IMRE), part of the Agency for Science, Technology, and Research (A*STAR), is looking for a research scientist to join the development of an integrated quantum photonics platform, with a focus on integrated single-photon detectors. The scientist will be heavily involved in developing the device...

  • Data Scientist

    5 days ago


    Singapore Amgen Full time

    Data ScientistAmgen Singapore ManufacturingHOW MIGHT YOU DEFY IMAGINATION?Amgen is one of the world's leading independent biotechnology companies. For over 4 decades, Amgen has pioneered biotechnology breakthroughs, to bring state-of-the-art medicines from laboratory to the patient. Amgen has not only discovered and developed innovative human therapeutics,...

  • Senior Data Scientist

    3 months ago


    Singapore DEZIRE TECHNOLOGIES Full time

    Roles & ResponsibilitiesMeasuring, monitoring, optimizing and recommending changes to productionized models.Managing infrastructure associated with machine learning and advanced analytics.Transforming and converting data science prototypes.Performing statistical analysis.Running machine learning tests including existing deployment improvements and new...

  • Senior Data Scientist

    4 weeks ago


    Singapore DEZIRE TECHNOLOGIES Full time

    Roles & ResponsibilitiesMeasuring, monitoring, optimizing and recommending changes to productionized models.Managing infrastructure associated with machine learning and advanced analytics.Transforming and converting data science prototypes.Performing statistical analysis.Running machine learning tests including existing deployment improvements and new...


  • Singapore ThermoFisher Scientific Full time

    Job DescriptionThe Scientist III, Molecular Biology, will take a leading role in verification and validation (V&V) and change validation of instrument systems with the emphasis on molecular biology and biochemistry. The successful candidate will provide technical expertise on a project and department level and will be encouraged to integrate into a...


  • Singapore KK WOMEN'S AND CHILDREN'S HOSPITAL PTE. LTD. Full time

    Roles & ResponsibilitiesThe Department of Pathology and Laboratory Medicine (Haematology Laboratory) at KK Women’s and Children’s Hospital currently has a vacancy for a Medical Laboratory Scientist / Senior Medical Laboratory Scientist. You will be an important member of the team providing scientific and technical input to the daily operations, process...


  • Singapore CTES CONSULTING PTE. LTD. Full time

    Roles & ResponsibilitiesOur client is actively searching for a Principal Data Scientist to join their team!If you are a dynamic individual seeking a new career opportunity, read further!The responsibilities of this role are:We are leading an AI Lab, pioneering in the field of artificial intelligence in healthcare. Our mission is to revolutionize the way AI...