Technologist, Cell Culture Development

Found in: Talent SG C2 - 3 weeks ago

Singapur, Singapore Lonza Full time

Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.

Did you know that we are the 1st biologics contract manufacturer in ? We offer you exposure to upcoming biotech and established pharmaceutical companies and to the manufacturing technology needed to produce mammalian treatments and cell therapies of tomorrow. Our global manufacturing network is recognized for its reliable, high-quality services, regulatory track record, global footprint, innovative technology platforms and extensive experience – we, in Singapore are proud to be part of this global network.

As a Technologist you will be joining Cell Culture Development team within the Development Services in Lonza Singapore. This group is responsible for the development and characterization of manufacturing processes used for the production of novel therapeutic recombinant proteins for Lonza’s global client base. The purpose of this role is to execute process development and process characterization activities (BLA studies).

The successful applicant for this position will be joining Cell Culture Development team in Lonza Singapore. This group is responsible for the development and characterization of manufacturing processes used for the production of novel therapeutic recombinant proteins for Lonza’s global client base. The purpose of this role is to support our scientists in process development and characterization activities at laboratory scale.

Duties and Responsibilities include:

To work to the highest scientific standards to support our scientists and projects

To perform hands-on laboratory work in the mammalian cell culture process development team contributing to the development of processes. For example,

Perform routine cell culture activities in multi-well plates, deep-well plate and shake flasks.

Assist in cell line generation activities including transfection and cloning (using Beacon® Optofluidic System)

Assist in the operation of automated miniature bioreactor systems (Ambr15 or Ambr250), rocking bioreactors and 10L laboratory scale bioreactors. Perform daily culture performance monitoring and analysis using pH meter, osmometer, Nova Flex 2, Vi-Cell

Prepare media and buffers.

Capture process data, review and report these data to internal teams.

Perform activities in accordance with Standard Operating Procedures (SOPs) and study protocols.

Support daily operation and running of the laboratory, e.g. maintaining of equipment and management of inventory.

Perform regular housekeeping and help with maintaining 6S standards in the workplace.

Actively identify and deliver operational efficiency projects to improve efficient running of the department.

Contribute to departmental safety and training programs.

The role may require occasional weekend work.

Education and Experience:

Diploma/Bachelor in a relevant Science field or Equivalent.

The final role offered will be commensurate with the candidate’s experience.

Understand basic theories for mammalian cell culture and bioprocessing. Ability to apply these theories during laboratory operations. Practical laboratory experience in automated bioreactor system operation is highly advantageous.

Understanding of cGMP regulations will be advantageous.

Good communication skills (verbal and written).

Ability to work well in teams.

Demonstrates ability to motivate through enthusiasm.

Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.

People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.

Reference: R59441

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