Research Associate

6 months ago


Singapur, Singapore Nanyang Technological University Full time

Research Associate in Asst Prof Xia Yun's lab at LKCMedicine.

The appointed Research Associate will be based at the Lee Kong Chian School of Medicine, located in the Clinical Sciences Building Novena campus. LKCMedicine has a broad range of research programs and interdisciplinary research centers that host a range of leading research teams to conduct frontier biomedical research. Dr Xia’s group is internationally recognized for its contribution in the research area of human stem cell derived kidney organoids. To establish kidney organoids that are suitable for disease modeling and drug validation, Dr Xia’s group employed a multidisciplinary approach, including stem cell differentiation, multicellular self-organization, scRNAseq, high-content imaging, genetic perturbation, xenotransplantation, and etc. Key projects in Dr Xia’s group includes testing drugs for treating PKD in organoid xenograft models, modeling ccRCC initiation using gene edited kidney organoids, and establishing organoid models for studying diabetic kidney disease, etc. Ultimately, Dr Xia’s group aims to translate basic research outcome into therapeutic methodologies that can benefit patients. To accomplish this, Dr. Xia’s team actively seeks industrial and clinical collaborations to promote translational science.

The appointed Research Associate is expected to play an important role in the project entitled “Preclinical evaluation of candidate PKD drugs in kidney organoid xenograft model and genetic animal model”.

Key responsibilities:

Liaise with industrial collaborators and coordinate collaboration between academia and industry and promote industrialization of research outcome of this project.

Responsible for lab animal husbandry, genotyping, and experimentation.

Perform animal tissue collection, procession, and imaging.

Request quotation, negotiate price, prepare purchasing request, update purchasing record, prepare safety issue related paperwork (BPN and IACUC applications).

Prepare the inventory lists for lab regents, cell lines, animal breeding record. Assign lab duties to lab personnel.

Key competencies and requirements:

Master’s degree in relevant field of molecular and cell biology, biochemistry, biotechnology, bioengineering, or other life sciences preferred.

Substantial experience in industry is advantageous as the role requires laising with industrial collaborators and coordinate collaboration between academia and industry and promote industrialization of research outcome of this project.

Proven track records of working independently and collaborate effectively in a highly diverse and interdisciplinary team and working with colleagues/collaborators from different education and training background is essential.

Prior knowledge in animal experimentation is preferred. Experimental skills in molecular biology (CRISPR-Cas9 gene editing tool) and biochemistry will be adding an advantage.

Self-motivated and well-organized with good communication and technical skills.

Hiring Institution: LKC

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