Senior Scientist, Development Services
3 months ago
Today, Lonza is a global leader in life sciences operating across three continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our people own their careers. Their ideas, big and small, genuinely improve the world. And that’s the kind of work we want to be part of.
Did you know that we are the 1st biologics contract manufacturer in ? We offer you exposure to upcoming biotech and established pharmaceutical companies and to the manufacturing technology needed to produce mammalian treatments and cell therapies of tomorrow. Our global manufacturing network is recognized for its reliable, high-quality services, regulatory track record, global footprint, innovative technology platforms and extensive experience – we, in Singapore are proud to be part of this global network.
The successful applicant for this position will be joining Purification Development team in Development Services, Lonza Singapore. As a Senior Scientist , you will be able to develop and enhance your technical and scientific capabilities as well as build on your technical leadership skills. You will be involved in hands-on experimental activities as well as supporting projects right from planning to delivery.
Duties and Responsibilities include:
Perform hands-on laboratory work in the purification process development team contributing or leading the development of processes suitable for technology transfer to the cGMP manufacturing teams. An understanding of cGMP manufacturing facility constraints and their impact on development activities will be developed.
Lead the junior scientists in the team for Process Development/Process Validation / Process Characterization activities, including experimental designing, planning, supervising and directing studies.
Process Characterization activities including Risk Assessment (FMEA), employing DoE methodologies, data analysis and interpretation to define process parameter ranges and process steps.
Draft and review high quality technical documents- Protocols, reports, SOPs etc.
Be the project representative delivering high-quality communication to ensure an outstanding customer experience (written documents, telecons, face to face meetings).
Working as an integral part of a site and global project team, co-ordinate multiple projects and ensure timely delivery of project work stages.
Purification activities include Chromatography (Affinity, Mixed-mode, ion exchange) using the AKTA purification system, Ultrafiltration/diafiltration and viral reduction strategies.
Train new hires and junior scientists with existing/new technologies.
Work with the highest scientific standards under the direction of the Line Manager.
Communicate project updates to internal stake holders and external customers.
Contribute to the efficient running of the department including instigating and delivering operational efficiency projects.
Contribute to departmental safety and training programs as required.
Technical supervision of projects and project teams may be required.
Education Experience
Degree/PhD in a relevant Science field or equivalent.
Minimum 4 years' work experience in relevant field or PhD with 2 years postdoctoral/ 3 years of industrial experience.
The final role offered will be commensurate with the candidate’s experience.
Expertise with relevant years of experience in protein purification process development.
Experience in Process Characterization/Process Validation, involving the use of statistical software for experimental design and data analysis will be highly advantageous.
Understanding of cGMP regulations will be advantageous.
Excellent technical writing skills.
Excellent communication skills (verbal and written).
Good problem solving and analytical skills.
Good team working skills.
Every day, Lonza’s products and services have a positive impact on millions of people. For us, this is not only a great privilege, but also a great responsibility. How we achieve our business results is just as important as the achievements themselves. At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically.
People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world. The satisfaction that comes with making a meaningful difference.
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Reference: R60637-
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